Stem cell dynamics, migration and plasticity during wound healing

被引:287
作者
Dekoninck, Sophie [1 ]
Blanpain, Cedric [1 ,2 ]
机构
[1] Univ Libre Bruxelles, Lab Stem Cells & Canc, Brussels, Belgium
[2] Univ Libre Bruxelles, WELBIO, Brussels, Belgium
基金
欧洲研究理事会;
关键词
LABEL-RETAINING CELLS; HAIR FOLLICLE REGENERATION; PROGENITOR CELLS; BETA-CATENIN; MOUSE SKIN; POPULATION; DISTINCT; REPAIR; LINEAGE; MORPHOGENESIS;
D O I
10.1038/s41556-018-0237-6
中图分类号
Q2 [细胞生物学];
学科分类号
071009 ; 090102 ;
摘要
Tissue repair is critical for animal survival. The skin epidermis is particularly exposed to injuries, which necessitates rapid repair. The coordinated action of distinct epidermal stem cells recruited from various skin regions together with other cell types, including fibroblasts and immune cells, is required to ensure efficient and harmonious wound healing. A complex cross-talk ensures the activation, migration and plasticity of these cells during tissue repair.
引用
收藏
页码:18 / 24
页数:7
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