The Cardiovascular Research Network A New Paradigm for Cardiovascular Quality and Outcomes Research

被引：116

作者：

Go, Alan S. ^{[1
]}

Magid, David J. ^{[2
]}

Wells, Barbara ^{[3
]}

Sung, Sue Hee ^{[1
]}

Cassidy-Bushrow, Andrea E. ^{[4
]}

Greenlee, Robert T. ^{[5
]}

Langer, Robert D. ^{[6
]}

Lieu, Tracy A. ^{[7
,8
]}

Margolis, Karen L. ^{[9
]}

Masoudi, Frederick A. ^{[10
]}

McNeal, Catherine J. ^{[11
,12
]}

Murata, Glen H. ^{[13
,14
]}

Newton, Katherine M. ^{[15
,16
]}

Novotny, Rachel ^{[17
]}

Reynolds, Kristi ^{[18
]}

Roblin, Douglas W. ^{[19
,20
]}

Smith, David H. ^{[16
,21
,22
]}

Vupputuri, Suma ^{[19
]}

White, Robert E. ^{[13
,23
]}

Olson, Jean ^{[3
]}

Rumsfeld, John S. ^{[24
]}

Gurwitz, Jerry H. ^{[25
,26
]}

机构：

[1] Univ Calif San Francisco, Kaiser Permanente No Calif, San Francisco, CA 94143 USA

[2] Univ Colorado, Kaiser Permanente Colorado, Denver, CO 80202 USA

[3] NHLBI, Bethesda, MD 20892 USA

[4] Henry Ford Hlth Syst, Detroit, MI USA

[5] Univ Wisconsin, Marshfield Clin Fdn Med Res & Educ, Madison, WI USA

[6] Geisinger Hlth Syst, Danville, PA USA

[7] Harvard Pilgrim Hlth Care, Dept Ambulatory Care & Prevent, Boston, MA USA

[8] Harvard Univ, Sch Med, Boston, MA USA

[9] Univ Minnesota, HealthPartners Res Fdn, Minneapolis, MN USA

[10] Denver Hlth Med Ctr, Denver, CO USA

[11] Scott & White Mem Hosp & Clin, Temple, TX USA

[12] Texas A&M Univ, Texas A&M Hlth Sci Ctr, College Stn, TX USA

[13] Univ New Mexico, Albuquerque, NM 87131 USA

[14] New Mexico VA Hlth Care Syst, Albuquerque, NM USA

[15] Grp Hlth Cooperat Puget Sound, Seattle, WA 98121 USA

[16] Univ Washington, Seattle, WA 98195 USA

[17] Univ Hawaii, Kaiser Permanente Ctr Hlth Res Hawaii, Honolulu, HI 96822 USA

[18] Kaiser Permanente So Calif, Pasadena, CA USA

[19] Kaiser Permanente Georgia, Atlanta, GA USA

[20] Emory Univ, Atlanta, GA 30322 USA

[21] Kaiser Permanente NW, Portland, OR USA

[22] Oregon State Univ, Corvallis, OR 97331 USA

[23] Lovelace Clin Fdn, Albuquerque, NM USA

[24] Denver Vet Affairs Med Ctr, Denver, CO USA

[25] Meyers Primary Care Inst & Fallon Community Hlth, Worcester, MA USA

[26] Univ Massachusetts, Amherst, MA 01003 USA

来源：

CIRCULATION-CARDIOVASCULAR QUALITY AND OUTCOMES | 2008年 / 1卷 / 02期

关键词：

cardiovascular disease; risk factors; outcomes; epidemiology; quality of care;

D O I：

10.1161/CIRCOUTCOMES.108.801654

中图分类号：

R5 [内科学];

学科分类号：

1002 [临床医学]; 100201 [内科学];

摘要：

Background-A clear need exists for a more systematic understanding of the epidemiology, diagnosis, and management of cardiovascular diseases. More robust data are also needed on how well clinical trials are translated into contemporary community practice and the associated resource use, costs, and outcomes. Methods and Results-The National Heart, Lung, and Blood Institute recently established the Cardiovascular Research Network, which represents a new paradigm to evaluate the epidemiology, quality of care, and outcomes of cardiovascular disease and to conduct future clinical trials using a community-based model. The network includes 15 geographically distributed health plans with dedicated research centers, National Heart, Lung, and Blood Institute representatives, and an external collaboration and advisory committee. Cardiovascular research network sites bring complementary content and methodological expertise and a diverse population of approximate to 11 million individuals treated through various health care delivery models. Each site's rich electronic databases (eg, sociodemographic characteristics, inpatient and outpatient diagnoses and procedures, pharmacy, laboratory, and cost data) are being mapped to create a standardized virtual data warehouse to facilitate rapid and efficient large-scale research studies. Initial projects focus on (1) hypertension recognition and management, (2) quality and outcomes of warfarin therapy, and (3) use, outcomes, and costs of implantable cardioverter defibrillators. Conclusions-The Cardiovascular Research Network represents a new paradigm in the approach to cardiovascular quality of care and outcomes research among community-based populations. Its unique ability to characterize longitudinally large, diverse populations will yield novel insights into contemporary disease and risk factor surveillance, management, outcomes, and costs. The Cardiovascular Research Network aims to become the national research partner of choice for efforts to improve the prevention, diagnosis, treatment, and outcomes of cardiovascular diseases. (Circ Cardiovasc Qual Outcomes. 2008;1:138-147.)

引用

页码：138 / 147

页数：10

共 43 条

[1]

Characteristics and outcomes of patients hospitalized for heart failure in the United States: Rationale, design, and preliminary observations from the first 100,000, cases in the Acute Decompensated Heart Failure National Registry (ADHERE) [J].

Adams, KF ;

Fonarow, GC ;

Emerman, CL ;

LeJemtel, TH ;

Costanzo, MR ;

Abraham, WT ;

Berkowitz, RL ;

Galvao, M ;

Horton, DP .

AMERICAN HEART JOURNAL, 2005, 149 (02) :209-216

[2]

Rationale and design of the GRACE (Global Registry of Acute Coronary Events) Project:: A multinational registry of patients hospitalized with acute coronary syndromes [J].

Agnelli, G ;

Avezum, A ;

Brieger, D ;

Budaj, A ;

Cannon, CP ;

Goldberg, RJ ;

Goodman, S ;

Gulba, DC ;

Granger, C ;

Kennelly, BM ;

Gurfinkel, E ;

López-Sendón, J ;

Klein, W ;

Montalescot, G ;

Van de Werf, F .

AMERICAN HEART JOURNAL, 2001, 141 (02) :190-199

[3]

*AM HEART ASS, AM HEART ASS STRAT G

[4]

[Anonymous], 2000, HLTH PEOPL 2010, V1

[5]

The pharmacology and management of the vitamin K antagonists [J].

Ansell, J ;

Hirsh, J ;

Poller, L ;

Bussey, H ;

Jacobson, A ;

Hylek, E .

CHEST, 2004, 126 (03) :204S-233S

[6]

Bardy GH, 2005, NEW ENGL J MED, V352, P2146

[7]

Cardiovascular events associated with rofecoxib in a colorectal adenoma chemoprevention trial [J].

Bresalier, RS ;

Sandler, RS ;

Quan, H ;

Bolognese, JA ;

Oxenius, B ;

Horgan, K ;

Lines, C ;

Riddell, R ;

Morton, D ;

Lanas, A ;

Konstam, MA ;

Baron, JA .

NEW ENGLAND JOURNAL OF MEDICINE, 2005, 352 (11) :1092-1102

[8]

Brindis R G, 2001, J Am Coll Cardiol, V37, P2240, DOI 10.1016/S0735-1097(01)01372-9

[9]

ACC/AHA/HRS 2006 Key Data Elements and Definitions for Electrophysiological Studies and Procedures A Report of the American College of Cardiology/American Heart Association Task Force on Clinical Data Standards (ACC/AHA/HRS Writing Committee to Develop Data Standards on Electrophysiology) [J].

Buxton, Alfred E. ;

Calkins, Hugh ;

Callans, David J. ;

DiMarco, John P. ;

Fisher, John D. ;

Greene, H. Leon ;

Haines, David E. ;

Hayes, David L. ;

Heidenreich, Paul A. ;

Miller, John M. ;

Poppas, Athena ;

Prystowsky, Eric N. ;

Schoenfeld, Mark H. ;

Zimetbaum, Peter J. ;

Heidenreich, Paul A. ;

Goff, David C. ;

Grover, Frederick L. ;

Malenka, David J. ;

Peterson, Eric D. ;

Radford, Martha J. ;

Redberg, Rita F. .

CIRCULATION, 2006, 114 (23) :2534-2570

[10]

Seventh Report of the Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure [J].

Chobanian, AV ;

Bakris, GL ;

Black, HR ;

Cushman, WC ;

Green, LA ;

Izzo, JL ;

Jones, DW ;

Materson, BJ ;

Oparil, S ;

Wright, JT ;

Roccella, EJ .

HYPERTENSION, 2003, 42 (06) :1206-1252

← 1 2 3 4 5 →