Rearrangement of epoxides in non-aldol aldol process: Allylic vs. tertiary and secondary carbocationic centers

被引：57

作者：

Jung, ME ^{[1
]}

Marquez, R ^{[1
]}

机构：

[1] Univ Calif Los Angeles, Dept Chem & Biochem, Los Angeles, CA 90095 USA

来源：

TETRAHEDRON LETTERS | 1999年 / 40卷 / 16期

基金：

美国国家卫生研究院;

关键词：

D O I：

10.1016/S0040-4039(99)00458-X

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

It has been shown that allylic carbocations are formed in preference to tertiary or secondary carbocations in the rearrangement of substituted epoxides. However protection of the alkene as a bromo ether allows for the desired rearrangement and production of intermediates for the synthesis of the cytotoxic tedanolides. (C) 1999 Elsevier Science Ltd. All rights reserved.

引用

页码：3129 / 3132

页数：4

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