Special feature: Pharmacotherapy in personality disorders

被引:19
作者
Kapfhammer, HP [1 ]
Hippius, H [1 ]
机构
[1] Univ Munich, Dept Psychiat, D-80336 Munich, Germany
关键词
D O I
10.1521/pedi.1998.12.3.277
中图分类号
R749 [精神病学];
学科分类号
100205 ;
摘要
Recent epidemiological and psychobiological studies indicate that psychopharmacology is promising, even for the treatment of personality disorders. Psychotropic drugs may have positive effects on personality disorders that show a close relationship to Axis I disorders (e.g., schizotypal personality disorder-schizophrenia simplex; avoidant personality disorder-generalized social phobia; borderline personality disorder-affective disorders, etc.), In addition, psychotropic drugs may influence certain psychopathological symptom clusters (e.g., cognitive-perceptual organization, impulsivity/aggressivity, affective instability, anxiety/inhibition) present in various disorders. Psychotropic drugs may also be indicated when psychiatric comorbidity exists. The results of clinical pharmacological studies are reviewed with reference to cluster A, B, and C personality disorders. Some guidelines can be drawn from these trials, Clinically, the use of psychotropic drugs in symptomatic crises should be considered, especially when a secondary psychiatric comorbidity exists. Pharmacotherapy is well indicated for personality disorders closely associated with Axis I disorders. Usually pharmacotherapy is short term, although in some cases long-term treatment may be promising. However, pharmacotherapy must always refer to a supportive therapeutic interaction between physician and patient.
引用
收藏
页码:277 / 288
页数:12
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