Immunocytochemical localization of μ-opioid receptor in primary afferent neurons containing substance P or calcitonin gene-related peptide.: A light and electron microscope study in the rat

被引：69

作者：

Li, JL

Ding, YQ

Li, YQ

Li, JS

Nomura, S

Kaneko, T

Mizuno, N ^{[1
]}

机构：

[1] Tokyo Metropolitan Inst Neurosci, Off Director, Fuchu, Tokyo 1838526, Japan

[2] Fourth Mil Med Univ, Dept Anat, Xian 710032, Peoples R China

[3] Fourth Mil Med Univ, KK Leung Brain Res Ctr, Xian 710032, Peoples R China

[4] Kyoto Univ, Fac Med, Coll Med Technol, Kyoto 6068501, Japan

[5] Kyoto Univ, Fac Med, Dept Morphol Brain Sci, Kyoto 6068501, Japan

来源：

BRAIN RESEARCH | 1998年 / 794卷 / 02期

基金：

中国国家自然科学基金;

关键词：

mu-opioid receptor; substance P; calcitonin gene-related peptide; dorsal root ganglion; trigeminal ganglion; spinal cord; nociception; rat;

D O I：

10.1016/S0006-8993(98)00332-1

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

Co-expression of mu-opioid receptor-like immunoreactivity (MOR-LI) with substance P (SP)- or calcitonin gene-related (CGRP)-LI was observed in rat trigeminal and dorsal root ganglion neurons. In particular, MOR-LI was found in axon terminals with SP- or CGRP-LI in laminae I and II of the medullary and spinal dorsal horns. MOR may be implicated in modulation of release of SP and CGRP from primary sensory afferents. (C) 1998 Elsevier Science B.V. All rights reserved.

引用

页码：347 / 352

页数：6

共 33 条

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