Growing a living blood vessel: Insights for the second hundred years

被引:42
作者
Brewster, Luke P.
Bufallino, Dominick
Ucuzian, Areck
Greisler, Howard P. [1 ]
机构
[1] Loyola Univ, Med Ctr, Dept Surg, Maywood, IL 60153 USA
[2] Loyola Univ, Med Ctr, Dept Anat Cell Biol & Neurobiol, Maywood, IL 60153 USA
[3] Edward J Hines VA Hosp, Surg Serv, Maywood, IL USA
[4] Edward J Hines VA Hosp, Res Serv, Maywood, IL USA
关键词
tissue engineered blood vessels; bypass grafting;
D O I
10.1016/j.biomaterials.2007.07.048
中图分类号
R318 [生物医学工程];
学科分类号
0831 ;
摘要
Cardiovascular disease continues to be the leading cause of death worldwide, and the prevalence of cardiovascular disease has reached epidemic proportions worldwide. Not surprisingly this has led to an increasing number of vascular procedures annually. Unfortunately, the success of these procedures over time continues to limit their long-term effects. Biomedical engineering approaches to improve upon current prosthetic grafts, developing new prosthetic grafts, and creating tissue engineered blood vessels for clinical application offer hope of improving the durability of vascular interventions and improving patients' treatment for cardiovascular disease. (C) 2007 Elsevier Ltd. All rights reserved.
引用
收藏
页码:5028 / 5032
页数:5
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