Corticosteroids in the management of the paediatric epilepsies

被引:73
作者
Gupta, R [1 ]
Appleton, R [1 ]
机构
[1] Royal Liverpool Childrens NHS Trust, Dept Neurol, Roald Dahl EEG Unit, Liverpool L12 2AP, Merseyside, England
关键词
D O I
10.1136/adc.2004.051375
中图分类号
R72 [儿科学];
学科分类号
100202 ;
摘要
Corticosteroids ( predominantly prednisolone and hydrocortisone) and adrenocorticotropic hormone ( ACTH) have been used in the treatment of the epilepsies for over 50 years. 1 2 Over the past 30 years most reports have focused on epilepsy syndromes and epileptic encephalopathies resistant to treatment with the more conventional anticonvulsant and antiepileptic drugs (AEDs) and specifically West syndrome. There has been relatively little attention on the role of corticosteroids in treating other epilepsies.
引用
收藏
页码:379 / 384
页数:6
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共 74 条
[1]  
AICARDI J, 1988, DEV MED CHILD NEUROL, V30, P429
[2]  
Akanuma H, 1998, Rinsho Shinkeigaku, V38, P461
[3]  
Appleton R, 2000, BRIT MED J, V320, P1404
[4]   West syndrome: long-term prognosis and social aspects [J].
Appleton, RE .
BRAIN & DEVELOPMENT, 2001, 23 (07) :688-691
[5]  
Appleton RE, 1996, DEV MED CHILD NEUROL, V38, P278
[6]  
Baram TZ, 1996, PEDIATRICS, V97, P375
[7]   PATHOPHYSIOLOGY OF MASSIVE INFANTILE SPASMS - PERSPECTIVE ON THE PUTATIVE ROLE OF THE BRAIN ADRENAL AXIS [J].
BARAM, TZ .
ANNALS OF NEUROLOGY, 1993, 33 (03) :231-236
[8]   What are the reasons for the strikingly different approaches to the use of ACTH in infants with West syndrome? [J].
Baram, TZ .
BRAIN & DEVELOPMENT, 2001, 23 (07) :647-648
[9]   Neuroactive steroids and seizure susceptibility [J].
Beyenburg, S ;
Stoffel-Wagner, B ;
Bauer, J ;
Watzka, M ;
Blümcke, I ;
Bidlingmaier, F ;
Elger, CE .
EPILEPSY RESEARCH, 2001, 44 (2-3) :141-153
[10]   THE TREATMENT OF INFANTILE SPASMS BY CHILD NEUROLOGISTS [J].
BOBELE, GB ;
BODENSTEINER, JB .
JOURNAL OF CHILD NEUROLOGY, 1994, 9 (04) :432-435