Clean synthesis in water. Part 2: Uncatalysed condensation reaction of Meldrum's acid and aldehydes

被引:167
作者
Bigi, F [1 ]
Carloni, S [1 ]
Ferrari, L [1 ]
Maggi, R [1 ]
Mazzacani, A [1 ]
Sartori, G [1 ]
机构
[1] Univ Parma, Dipartimemto Chim Organ & Ind, I-43100 Parma, Italy
关键词
Meldrum's acid; water; uncatalysed reaction; Knoevenagel condensation; arylidene Meldrum's acid; environmentally benign synthesis;
D O I
10.1016/S0040-4039(01)00978-9
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
The environment-friendly condensation of Meldrum's acid and aromatic, heteroaromatic and hindered aliphatic aldehydes is performed carrying out the reaction in water at 75 degreesC for 2 h, avoiding the addition of any catalyst. (C) 2001 Elsevier Science Ltd. All rights reserved.
引用
收藏
页码:5203 / 5205
页数:3
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