Balancing the benefits of n-3 polyunsaturated fatty acids and the risks of methylmercury exposure from fish consumption

被引：195

作者：

Mahaffey, Kathryn R. ^{[2
]}

Sunderland, Elsie M. ^{[3
]}

Chan, Hing Man ^{[1
]}

Choi, Anna L.

Grandjean, Philippe ^{[3
,4
]}

Marien, Koenraad ^{[5
]}

Oken, Emily ^{[6
,7
]}

Sakamoto, Mineshi ^{[8
]}

Schoeny, Rita ^{[9
]}

Weihe, Pal

Yan, Chong-Huai ^{[10
]}

Yasutake, Akira ^{[11
]}

机构：

[1] Univ No British Columbia, Community Hlth Sci Program, Prince George, BC V2N 4Z9, Canada

[2] George Washington Univ, Sch Publ Hlth, Dept Occupat & Environm Hlth, Washington, DC USA

[3] Harvard Univ, Sch Publ Hlth, Dept Environm Hlth, Boston, MA 02115 USA

[4] Univ So Denmark, Inst Publ Hlth, Odense, Denmark

[5] Washington State Dept Hlth, Washington, DC USA

[6] Harvard Univ, Sch Med, Dept Populat Med, Boston, MA 02115 USA

[7] Harvard Pilgrim Hlth Care Inst, Boston, MA USA

[8] Natl Inst Minamata Dis, Dept Epidemiol, Fukuoka, Japan

[9] US Environm Protect Agcy, Off Water, Washington, DC USA

[10] Shanghai Jiao Tong Univ, Sch Med, Shanghai Key Lab Childrens Environm Hlth, XinHua Hosp, Shanghai 200030, Peoples R China

[11] Natl Inst Minamata Dis, Biochem Sect, Fukuoka, Japan

来源：

NUTRITION REVIEWS | 2011年 / 69卷 / 09期

关键词：

docosahexaenoic acid; eicosapentaenoic acid; fish; methylmercury; n-3 polyunsaturated fatty acids; ALPHA-LINOLENIC ACID; SEYCHELLES CHILD-DEVELOPMENT; PRENATAL MERCURY EXPOSURE; IN-UTERO EXPOSURE; DOCOSAHEXAENOIC ACID; METHYL MERCURY; HAIR MERCURY; POLYCHLORINATED-BIPHENYLS; COGNITIVE-DEVELOPMENT; PLACENTAL-TRANSFER;

D O I：

10.1111/j.1753-4887.2011.00415.x

中图分类号：

R15 [营养卫生、食品卫生]; TS201 [基础科学];

学科分类号：

100403 ;

摘要：

Fish and shellfish are widely available foods that provide important nutrients, particularly n-3 polyunsaturated fatty acids (n-3 PUFAs), to many populations globally. These nutrients, especially docosahexaenoic acid, confer benefits to brain and visual system development in infants and reduce risks of certain forms of heart disease in adults. However, fish and shellfish can also be a major source of methylmercury (MeHg), a known neurotoxicant that is particularly harmful to fetal brain development. This review documents the latest knowledge on the risks and benefits of seafood consumption for perinatal development of infants. It is possible to choose fish species that are both high in n-3 PUFAs and low in MeHg. A framework for providing dietary advice for women of childbearing age on how to maximize the dietary intake of n-3 PUFAs while minimizing MeHg exposures is suggested. (C) 2011 International Life Sciences Institute

引用

页码：493 / 508

页数：16

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