Hong Kong samples of the traditional Chinese medicine ''Fang Ji'' contain aristolochic acid toxins

被引：16

作者：

Zhu, M

Phillipson, JD

机构：

[1] CHINESE UNIV HONG KONG,DEPT PHARM,SHATIN,NT,HONG KONG

[2] UNIV LONDON,SCH PHARM,DEPT PHARMACOGNOSY,LONDON WC1N 1AX,ENGLAND

来源：

INTERNATIONAL JOURNAL OF PHARMACOGNOSY | 1996年 / 34卷 / 04期

关键词：

aristolochic acids I and II; Fang Ji; HPLC assay; microscopy; quality assurance; renal toxins; traditional Chinese medicine; Aristolochia fangchi Y C Wu ex L D Chou et S M Hwang; Cocculus spp; Stephania tetrandra S Moore;

D O I：

10.1076/phbi.34.4.283.13232

中图分类号：

Q94 [植物学];

学科分类号：

071001 ;

摘要：

''Fang Ji'' is a commonly used traditional Chinese medicine which includes several species of plants. Authentic samples of ''Fang Ji'' including five samples of Aristolochia species, four samples of Stephania tetrandra and two samples of Cocculus species were compared microscopically and chemically (TLC, HPLC) with nine samples of ''Fang Ji'' purchased from herbal shops in Hong Kong. The renal toxins aristolochic acids 1 and 11 were present in each of the nine purchased samples and six of them contained the combined acid yield of 0.11 to 1.07%. Four of these samples were of poor quality being contaminated with either soil, fungi or beetles.

引用

页码：283 / 289

页数：7

共 15 条

[1] [Anonymous], 1992, PHARMACOPOEIA PEOPLE
[2] Chen H, 1990, Zhongguo Zhong Yao Za Zhi, V15, P707
[3] CHOU LD, 1981, CHINESE PHARM B, V16, P117
[4] DESMET PAG, 1992, ADVERSE EFFECTS HERB, V1, P78
[5] Feng YX, 1983, ACTA PHARM SIN, V18, P849
[6] FENG YX, 1985, CHIN J PHARM ANAL, V5, P28
[7] FENG YX, 1982, ACTA PHARMACOL SINIC, V47, P521
[8] FENG YX, 1983, ACTA PHARMACOL SINIC, V18, P291
[9] HU YM, 1986, ACTA PHARMACOL SINIC, V21, P29
[10] Tang W., 1992, CHINESE DRUGS PLANT, P145

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