Five flavans from Mariscus psilostachys

被引:40
作者
Garo, E
Maillard, M
Antus, S
Mavi, S
Hostettmann, K
机构
[1] LAJOS KOSSUTH UNIV,LEHRSTUHL ORGAN CHEM,H-4010 DEBRECEN,HUNGARY
[2] UNIV LAUSANNE,INST PHARMACOGNOSIE & PHYTOCHIM,CH-1015 LAUSANNE,SWITZERLAND
[3] NATL HERBARIUM & BOT GARDEN,HARARE,ZIMBABWE
基金
匈牙利科学研究基金会;
关键词
Mariscus psilostachys; Cyperaceae; flavans; flavanones; fungicidal activity;
D O I
10.1016/S0031-9422(96)00526-2
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Phytochemical investigation of two batches of Mariscus psilostachys led to the isolation and characterization of five flavans and three flavanones. Two flavans are new natural products and their structures have been established as (2S)-4'-hydroxy-5,7,3'-trimethoxyflavan and (+/-)-5,4'-dihydroxy-7-3'-dimethoxyflavan. Absolute configuration of the optically active compound isolated has been determined on the basis of its CD spectrum. Antimicrobial activity against Candida albicans and Cladosporium cucumeriman were determined for all compounds. The less polar flavans showed to be more active in both TLC assays and dilution assays. Copyright (C) 1996 Elsevier Science Ltd
引用
收藏
页码:1265 / 1269
页数:5
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