Prognosis of hepatocellular carcinoma with diabetes mellitus after hepatic resection

被引:89
作者
Ikeda, Y [1 ]
Shimada, M [1 ]
Hasegawa, H [1 ]
Gion, T [1 ]
Kajiyama, K [1 ]
Shirabe, K [1 ]
Yanaga, K [1 ]
Takenaka, K [1 ]
Sugimachi, K [1 ]
机构
[1] Kyushu Univ, Dept Surg 2, Fac Med, Higashi Ku, Fukuoka 812, Japan
关键词
D O I
10.1002/hep.510270615
中图分类号
R57 [消化系及腹部疾病];
学科分类号
摘要
We evaluated the effect of diabetes mellitus on the prognosis of hepatocellular carcinoma after an elective hepatic resection, Of the 342 patients who underwent a hepatic resection between April 1985 and March 1995, 87 (25.4%) were diabetic. Postoperative morbidity was more common among diabetics than among nondiabetics (36.0% vs. 22.5%, P = .0239). The postoperative survival rate and the cancer-free survival rate were also better in patients without diabetes than in those with diabetes (P = .0333, P = .0149), The results of a multivariate analysis show diabetes mellitus to be an independent and prognostic indicator after a hepatic resection with hepatocellular carcinoma. According to the above findings, diabetes mellitus is thus considered to be a risk factor for prognosis after hepatic resection in patients with hepatocellular carcinoma.
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页码:1567 / 1571
页数:5
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