Novel software tools for chemical diversity

被引：232

作者：

Pearlman, RS ^{[1
]}

Smith, KM ^{[1
]}

机构：

[1] Univ Texas, Coll Pharm, Lab Mol Graph & Theoret Modelling, Austin, TX 78712 USA

来源：

PERSPECTIVES IN DRUG DISCOVERY AND DESIGN | 1998年 / 9-11卷

关键词：

D O I：

10.1023/A:1027232610247

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

引用

页码：339 / 353

页数：15

共 15 条

[1] Use of structure Activity data to compare structure-based clustering methods and descriptors for use in compound selection [J].

Brown, RD ;

Martin, YC .

JOURNAL OF CHEMICAL INFORMATION AND COMPUTER SCIENCES, 1996, 36 (03) :572-584

[2] MOLECULAR-IDENTIFICATION NUMBER FOR SUBSTRUCTURE SEARCHES [J].

BURDEN, FR .

JOURNAL OF CHEMICAL INFORMATION AND COMPUTER SCIENCES, 1989, 29 (03) :225-227

[3] (PHOSPHINYLOXY)ACYL AMINO-ACID INHIBITORS OF ANGIOTENSIN CONVERTING ENZYME .2. TERMINAL AMINO-ACID-ANALOGS OF (S)-1-[6-AMINO-2-[[HYDROXY(4-PHENYLBUTYL)PHOSPHINYL]OXY]-1-OXOHEXYL]-L-PROLINE [J].

KARANEWSKY, DS ;

BADIA, MC ;

CUSHMAN, DW ;

DEFORREST, JM ;

DEJNEKA, T ;

LEE, VG ;

LOOTS, MJ ;

PETRILLO, EW .

JOURNAL OF MEDICINAL CHEMISTRY, 1990, 33 (05) :1459-1469

[4] (PHOSPHINYLOXY)ACYL AMINO-ACID INHIBITORS OF ANGIOTENSIN CONVERTING ENZYME (ACE) .1. DISCOVERY OF (S)-1-[6-AMINO-2-[[HYDROXY(4-PHENYLBUTYL)PHOSPHINYL]OXY]-1-OXOHEXYL]-L-PROLINE, A NOVEL ORALLY ACTIVE INHIBITOR OF ACE [J].

KARANEWSKY, DS ;

BADIA, MC ;

CUSHMAN, DW ;

DEFORREST, JM ;

DEJNEKA, T ;

LOOTS, MJ ;

PERRI, MG ;

PETRILLO, EW ;

POWELL, JR .

JOURNAL OF MEDICINAL CHEMISTRY, 1988, 31 (01) :204-212

[5] ANGIOTENSIN-CONVERTING ENZYME-INHIBITORS - MERCAPTAN, CARBOXYALKYL DIPEPTIDE, AND PHOSPHINIC ACID INHIBITORS INCORPORATING 4-SUBSTITUTED PROLINES [J].

KRAPCHO, J ;

TURK, C ;

CUSHMAN, DW ;

POWELL, JR ;

DEFORREST, JM ;

SPITZMILLER, ER ;

KARANEWSKY, DS ;

DUGGAN, M ;

ROVNYAK, G ;

SCHWARTZ, J ;

NATARAJAN, S ;

GODFREY, JD ;

RYONO, DE ;

NEUBECK, R ;

ATWAL, KS ;

PETRILLO, EW .

JOURNAL OF MEDICINAL CHEMISTRY, 1988, 31 (06) :1148-1160

[6] ANGIOTENSIN CONVERTING ENZYME-INHIBITORS - (MERCAPTOAROYL)AMINO ACIDS [J].

MENARD, PR ;

SUH, JT ;

JONES, H ;

LOEV, B ;

NEISS, ES ;

WILDE, J ;

SCHWAB, A ;

MANN, WS .

JOURNAL OF MEDICINAL CHEMISTRY, 1985, 28 (03) :328-332

[7]

PATCHETT AA, 1980, NATURE, V288, P280, DOI 10.1038/288280a0

[8]

PEARLMAN RE, UNPUB

[9]

PEARLMAN RS, 1996, NETSCI, V2, P1

[10]

PEARLMAN RS, 1996, DIVERSESOLUTIONS USE

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