Analysis of proton-proton transfer dynamics in rotating solids and their use for 3D structure determination

被引：117

作者：

Lange, A ^{[1
]}

Seidel, K ^{[1
]}

Verdier, L ^{[1
]}

Luca, S ^{[1
]}

Baldus, M ^{[1
]}

机构：

[1] Max Planck Inst Biophys Chem, Dept NMR Based Struct Biol, D-37077 Gottingen, Germany

来源：

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY | 2003年 / 125卷 / 41期

关键词：

D O I：

10.1021/ja034555g

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A detailed analysis of proton-proton-transfer dynamics under magic angle spinning NMR is presented. Results obtained on model compounds are evaluated under different experimental conditions and NMR mixing schemes. It is shown that the resulting buildup rates can be interpreted in terms of internuclear proton-proton distances provided that an appropriate theoretical description is chosen. As demonstrated in two test applications, these dependencies can be used in the context of a three-dimensional structure determination in the solid state.

引用

页码：12640 / 12648

页数：9

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