Sample collection guidelines for trace elements in blood and urine

被引:109
作者
Cornelis, R
Heinzow, B
Herber, RFM
Christensen, JM
Poulsen, OM
Sabbioni, E
Templeton, DM
Thomassen, Y
Vahter, M
Vesterberg, O
机构
[1] INST ENVIRONM TOXICOL SCHLESWIG HOLSTEIN,D-2300 KIEL,GERMANY
[2] UNIV AMSTERDAM,CORONEL LAB OCCUPAT & ENVIRONM HLTH,NL-1105 AZ AMSTERDAM,NETHERLANDS
[3] NATL INST OCCUPAT HLTH,DK-2100 COPENHAGEN O,DENMARK
[4] EC RES CTR,ENVIRONM TOXICOL UNIT,CCR,I-21020 ISPRA,ITALY
[5] UNIV TORONTO,DEPT CLIN BIOCHEM,TORONTO,ON M5G 1L5,CANADA
[6] NATL INST OCCUPAT HLTH,N-0033 OSLO,NORWAY
[7] KAROLINSKA INST ENVIRONM MED,S-17177 STOCKHOLM,SWEDEN
[8] NATL INST OCCUPAT HLTH,S-17184 SOLNA,SWEDEN
关键词
trace elements; blood; urine; sample collection; Al; As; Cd; Cr; Co; Cu; Pb; Li; Mn; Hg; Ni; Se; Zn;
D O I
10.1016/S0946-672X(96)80018-6
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
This paper presents an organized system for element-specific sample collection and handling of human blood (whole blood, serum or plasma, packed cells or erythrocytes) and urine also indicating a proper definition of the subject and sample. Harmonized procedures for collection, preparation, analysis and quality control are suggested. The aim is to assist scientists worldwide to produce comparable data which will be useful on a regional, national and international scale. The guidelines are directed to the elements aluminium, arsenic, cadmium, chromium, cobalt, copper, lead, lithium, manganese, mercury, nickel, selenium and zinc. These include the most important elements measured for their occupational or clinical significance, and serve as examples of principles that will guide development of methods for other elements in the future.
引用
收藏
页码:103 / 127
页数:25
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