Monte Carlo and TLD dosimetry of an 192Ir high dose-rate brachytherapy source

被引:87
作者
Karaiskos, P [1 ]
Angelopoulos, A
Sakelliou, L
Sandilos, P
Antypas, C
Vlachos, L
Koutsouveli, E
机构
[1] Univ Athens, Dept Phys, Nucl & Particle Phys Sect, GR-15771 Athens, Greece
[2] Univ Athens, Areteion Hosp, Sch Med, Dept Radiol, Athens 11528, Greece
[3] Hygeia Hosp, Dept Phys Med, Athens 15123, Greece
关键词
Ir-192; high dose rate brachytherapy; anisotropy; Monte Carlo; TLD;
D O I
10.1118/1.598371
中图分类号
R8 [特种医学]; R445 [影像诊断学];
学科分类号
1002 ; 100207 ; 1009 ;
摘要
An analytical Monte Carlo simulation code has been used to perform dosimetry calculations around an Ir-192 high dose-rate brachytherapy source utilized in the widely used microSelectron afterloaded system. Radial dose functions, dose rate constant and anisotropy functions, utilized in the AAPM Task Group 43 dose estimation formalism, have been calculated. In addition, measurements of anisotropy functions using LiF TLD-100 rods have been performed in a polystyrene phantom to support our Monte Carlo calculations. The energy dependence of LiF TLD response was investigated over the whole range of measurement distances and angles. TLD measurements and Monte Carlo calculations are in agreement to each other and agree with published data. The influence of phantom dimensions on calculations was also investigated. Radial dose functions were found to depend significantly on phantom dimensions at radial distances near phantom edges. Deviations of up to 25% are observed at these distances due to the lack of full scattering conditions, indicating that body dimensions should be taken into account in treatment planning when the absorbed dose is calculated near body edges. On the other hand, anisotropy functions do not demonstrate a strong dependence on phantom dimensions. However, these functions depend on radial distance at angles close to the longitudinal axis of the source, where deviations of up to 20% are observed. (C) 1998 American Association of Physicists in Medicine. [S0094-2405(98)00310-1].
引用
收藏
页码:1975 / 1984
页数:10
相关论文
共 41 条
[1]  
ANDERSON L, 1990, INTERSTITIAL BRACHYT
[2]   ACCURATE MONTE-CARLO CALCULATIONS OF THE COMBINED ATTENUATION AND BUILDUP FACTORS, FOR ENERGIES (20-1500 KEV) AND DISTANCES (0-10 CM) RELEVANT IN BRACHYTHERAPY [J].
ANGELOPOULOS, A ;
PERRIS, A ;
SAKELLARIOU, K ;
SAKELLIOU, L ;
SARIGIANNIS, K ;
ZARRIS, G .
PHYSICS IN MEDICINE AND BIOLOGY, 1991, 36 (06) :763-778
[3]   Fetal dose evaluation during breast cancer radiotherapy [J].
Antypas, C ;
Sandilos, P ;
Kouvaris, J ;
Balafouta, E ;
Karinou, E ;
Kollaros, N ;
Vlahos, L .
INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 1998, 40 (04) :995-999
[4]  
BALTAS D, 1993, 3 NUCL
[5]  
Berger M.J., 1963, METHODS COMPUTATIONA, P135
[6]  
BIELAJEW AF, 1987, NUCL INSTRUM METH B, V18, P165
[7]   A GENERAL THEORY OF CAVITY IONISATION [J].
BURLIN, TE .
BRITISH JOURNAL OF RADIOLOGY, 1966, 39 (466) :727-&
[8]  
CERRA F, 1990, ENDOCUR HYPERTHER ON, V6, P71
[9]   PHYSICAL CHARACTERISTICS OF SCATTERED RADIATION IN DIAGNOSTIC-RADIOLOGY - MONTE-CARLO SIMULATION STUDIES [J].
CHAN, HP ;
DOI, K .
MEDICAL PHYSICS, 1985, 12 (02) :152-165