Shared regulatory elements in the promoters of MHC class I and class II genes

被引：95

作者：

van den Elsen, PJ ^{[1
]}

Peijnenburg, A ^{[1
]}

van Eggermond, MCJA ^{[1
]}

Gobin, SJP ^{[1
]}

机构：

[1] Leiden Univ, Med Ctr, Dept Immunohaematol & Blood Bank, Div Mol Biol, NL-2300 RC Leiden, Netherlands

来源：

IMMUNOLOGY TODAY | 1998年 / 19卷 / 07期

关键词：

D O I：

10.1016/S0167-5699(98)01287-0

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

The finding that the major histocompatibility complex (MHC) class II trans-activator (CIITA) gene product plays a role in the regulation of transcription of MHC class I genes suggests a common regulation of transcription of class I and class II genes. Here, Peter van den Elsen and colleagues argue that the RFX complex also plays a role in the regulation of transcription of class I genes.

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页码：308 / 312

页数：5

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