The Chlamydomonas genome reveals the evolution of key animal and plant functions

被引：1982

作者：

Merchant, Sabeeha S.

Prochnik, Simon E.

Vallon, Olivier

Harris, Elizabeth H.

Karpowicz, Steven J.

Witman, George B.

Terry, Astrid

Salamov, Asaf

Fritz-Laylin, Lillian K.

Marechal-Drouard, Laurence

Marshall, Wallace F.

Qu, Liang-Hu

Nelson, David R.

Sanderfoot, Anton A.

Spalding, Martin H.

Kapitonov, Vladimir V.

Ren, Qinghu

Ferris, Patrick

Lindquist, Erika

Shapiro, Harris

Lucas, Susan M.

Grimwood, Jane

Schmutz, Jeremy

Cardol, Pierre

Cerutti, Heriberto

Chanfreau, Guillaume

Chen, Chun-Long

Cognat, Valerie

Croft, Martin T.

Dent, Rachel

Dutcher, Susan

Fernandez, Emilio

Fukuzawa, Hideya

Gonzalez-Ballester, David

Gonzalez-Halphen, Diego

Hallmann, Armin

Hanikenne, Marc

Hippler, Michael

Inwood, William

Jabbari, Kamel

Kalanon, Ming

Kuras, Richard

Lefebvre, Paul A.

Lemaire, Stephane D.

Lobanov, Alexey V.

Lohr, Martin

Manuell, Andrea

Meier, Iris

Mets, Laurens

Mittag, Maria

机构：

[1] US DOE, Joint Genome Inst, Walnut Creek, CA 94598 USA

[2] Univ Calif Los Angeles, Dept Chem & Biochem, Los Angeles, CA 90095 USA

[3] Univ Paris 06, CNRS, Inst Biol Physicochim, F-75005 Paris, France

[4] Duke Univ, Dept Biol, Durham, NC 27708 USA

[5] Univ Massachusetts, Sch Med, Dept Cell Biol, Worcester, MA 01655 USA

[6] Univ Calif Berkeley, Dept Mol & Cell Biol, Berkeley, CA 94720 USA

[7] CNRS, Inst Biol Mol Plantes, F-67084 Strasbourg, France

[8] Univ Calif San Francisco, Dept Biochem & Biophys, San Francisco, CA 94143 USA

[9] Zhongshan Univ, Biotechnol Res Ctr, Guangzhou 510275, Peoples R China

[10] Univ Tennessee, Dept Mol Sci, Memphis, TN 38163 USA

[11] Univ Tennessee, Ctr Excellence Genom & Bioinformat, Memphis, TN 38163 USA

[12] Univ Minnesota, Dept Plant Biol, St Paul, MN 55108 USA

[13] Iowa State Univ, Dept Genet Dev & Cell Biol, Ames, IA 50011 USA

[14] Genet Informat Res Inst, Mountain View, CA 94043 USA

[15] Inst Genom Res, Rockville, MD 20850 USA

[16] Salk Inst Biol Studies, Plant Biol Lab, La Jolla, CA 92037 USA

[17] Stanford Univ, Sch Med, Stanford Human Genome Ctr, Palo Alto, CA 94304 USA

[18] Univ Liege, Inst Plant Biol, Dept Life Sci, B-4000 Liege, Belgium

[19] Univ Nebraska, Sch Biol Sci Plant Sci Initiat, Lincoln, NE 68588 USA

[20] Univ Cambridge, Dept Plant Sci, Cambridge CB2 3EA, England

[21] Univ Calif Berkeley, Dept Plant & Mol Biol, Berkeley, CA 94720 USA

[22] Washington Univ, Sch Med, Dept Genet, St Louis, MO 63110 USA

[23] Univ Cordoba, Fac Ciencias, Dept Bioquim & Biol Mol, E-14071 Cordoba, Argentina

[24] Kyoto Univ, Grad Sch Biostudies, Kyoto 6068502, Japan

[25] Carnegie Inst, Dept Plant Biol, Stanford, CA 94306 USA

[26] Univ Nacl Autonoma Mexico, Inst Fisiol Celular, Dept Genet Mol, Mexico City 04510, DF, Mexico

[27] Univ Bielefeld, Dept Celluar & Dev Biol Plants, D-33615 Bielefeld, Germany

[28] Univ Munster, Inst Plant Biochem & Biotechnol, Dept Biol, D-48143 Munster, Germany

[29] Ecole Normale Super, CNRS, UMR 8186, Dept Biol, F-75230 Paris, France

[30] Univ Melbourne, Sch Bot, Plant Cell Biol Res Ctr, Melbourne, Vic 3010, Australia

[31] Univ Paris Sud, Inst Biotechnol Plantes, CNRS, UMR 8618, Orsay, France

[32] Univ Nebraska, N151 Beadle Ctr, Dept Biochem, Lincoln, NE 68588 USA

[33] Johannes Gutenberg Univ Mainz, Inst Allgemeine Bot, D-55099 Mainz, Germany

[34] Scripps Clin & Res Inst, Dept Cell Biol, La Jolla, CA 92037 USA

[35] Scripps Clin & Res Inst, Skaggs Inst Chem Biol, La Jolla, CA 92037 USA

[36] Ohio State Univ, PCMB & Plant Biotechnol Ctr, Columbus, OH 43210 USA

[37] Univ Chicago, Chicago, IL 60637 USA

[38] Univ Jena, Inst Allgemeine Bot & Pflanzenphysiol, D-07743 Jena, Germany

[39] Univ Arizona, Dept Mol & Cellular Biol, Tucson, AZ 85721 USA

[40] Louisiana State Univ, Dept Biol Sci, Baton Rouge, LA 70803 USA

[41] Univ Arizona, Dept Plant Sci, Tucson, AZ 85721 USA

[42] Univ New Brunswick, Dept Biol, Fredericton, NB E3B 6E1, Canada

[43] Univ Massachusetts, Sch Med, Dept Physiol, Worcester, MA 01605 USA

[44] UCL, Dept Biol, London WC1E 6BT, England

[45] Univ Sci & Technol Lille, IFR 118, CNRS, UMR 8576,Unite Glycobiol Struct & Fonctionnelle, Lille, France

[46] Univ Potsdam, Inst Biochem & Biol, D-14476 Golm, Germany

[47] Natl Jewish Med & Res Ctr, Dept Med, Denver, CO 80206 USA

[48] Univ Delaware, Delaware Biotechnol Inst, Newark, DE 19711 USA

[49] Inst Biol 2 Plant Biochem, D-79104 Freiburg, Germany

[50] Cornell Univ, Boyce Thompson Inst Plant Res, Ithaca, NY 14853 USA

来源：

SCIENCE | 2007年 / 318卷 / 5848期

关键词：

D O I：

10.1126/science.1143609

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

Chlamydomonas reinhardtii is a unicellular green alga whose lineage diverged from land plants over 1 billion years ago. It is a model system for studying chloroplast-based photosynthesis, as well as the structure, assembly, and function of eukaryotic flagella (cilia), which were inherited from the common ancestor of plants and animals, but lost in land plants. We sequenced the similar to 120-megabase nuclear genome of Chlamydomonas and performed comparative phylogenomic analyses, identifying genes encoding uncharacterized proteins that are likely associated with the function and biogenesis of chloroplasts or eukaryotic flagella. Analyses of the Chlamydomonas genome advance our understanding of the ancestral eukaryotic cell, reveal previously unknown genes associated with photosynthetic and flagellar functions, and establish links between ciliopathy and the composition and function of flagella.

引用

页码：245 / 251

页数：7

共 55 条

[1] Basal body dysfunction is a likely cause of pleiotropic Bardet-Biedl syndrome
Ansley, SJ
Badano, JL
Blacque, OE
Hill, J
Hoskins, BE
Leitch, CC
Kim, JC
Ross, AJ
Eichers, ER
Teslovich, TM
Mah, AK
Johnsen, RC
Cavender, JC
Lewis, RA
Leroux, MR
Beales, PL
Katsanis, N
[J]. NATURE, 2003, 425 (6958) : 628 - 633
[2] The genome of the diatom Thalassiosira pseudonana:: Ecology, evolution, and metabolism
Armbrust, EV
Berges, JA
Bowler, C
Green, BR
Martinez, D
Putnam, NH
Zhou, SG
Allen, AE
Apt, KE
Bechner, M
Brzezinski, MA
Chaal, BK
Chiovitti, A
Davis, AK
Demarest, MS
Detter, JC
Glavina, T
Goodstein, D
Hadi, MZ
Hellsten, U
Hildebrand, M
Jenkins, BD
Jurka, J
Kapitonov, VV
Kröger, N
Lau, WWY
Lane, TW
Larimer, FW
Lippmeier, JC
Lucas, S
Medina, M
Montsant, A
Obornik, M
Parker, MS
Palenik, B
Pazour, GJ
Richardson, PM
Rynearson, TA
Saito, MA
Schwartz, DC
Thamatrakoln, K
Valentin, K
Vardi, A
Wilkerson, FP
Rokhsar, DS
[J]. SCIENCE, 2004, 306 (5693) : 79 - 86
[3] Decoding cilia function: Defining specialized genes required for compartmentalized cilia biogenesis
Avidor-Reiss, T
Maer, AM
Koundakjian, E
Polyanovsky, A
Keil, T
Subramaniam, S
Zuker, CS
[J]. CELL, 2004, 117 (04) : 527 - 539
[4] SPERMIOGENESIS IN THE MOSS AULACOMNIUM PALUSTRE
BERNHARD, DL
RENZAGLIA, KS
[J]. BRYOLOGIST, 1995, 98 (01) : 52 - 70
[5] Photosynthetic eukaryotes unite: endosymbiosis connects the dots
Bhattacharya, D
Yoon, HS
Hackett, JD
[J]. BIOESSAYS, 2004, 26 (01) : 50 - 60
[6] Loss of C-elegans BBS-7 and BBS-8 protein function results in cilia defects and compromised intraflagellar transport
Blacque, OE
Reardon, MJ
Li, CM
McCarthy, J
Mahjoub, MR
Ansley, SJ
Badano, LL
Mah, AK
Beales, PL
Davidson, WS
Johnsen, RC
Audeh, M
Plasterk, RHA
Baillie, DL
Katsanis, N
Quarmby, LM
Wicks, SR
Leroux, MR
[J]. GENES & DEVELOPMENT, 2004, 18 (13) : 1630 - 1642
[7] More than one way to build a flagellum: comparative genomics of parasitic protozoa
Briggs, LJ
Davidge, JA
Wickstead, B
Ginger, ML
Gull, K
[J]. CURRENT BIOLOGY, 2004, 14 (15) : R611 - R612
[8] Toward automatic reconstruction of a highly resolved tree of life
Ciccarelli, FD
Doerks, T
von Mering, C
Creevey, CJ
Snel, B
Bork, P
[J]. SCIENCE, 2006, 311 (5765) : 1283 - 1287
[9] A defect in coenzyme Q biosynthesis is responsible for the respiratory deficiency in Saccharomyces cerevisiae abc1 mutants
Do, TQ
Hsu, AY
Jonassen, T
Lee, PT
Clarke, CF
[J]. JOURNAL OF BIOLOGICAL CHEMISTRY, 2001, 276 (21) : 18161 - 18168
[10] *DOE JOINT GEN I, CHLAM REINH V 3 0

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