Development and evaluation of an Epstein-Barr virus (EBV) immunoglobulin m enzyme-linked immunosorbent assay based on the 18-kilodalton matrix protein for diagnosis of primary EBV infection

被引：13

作者：

Chan, KH

Luo, RX

Chen, HL

Ng, MH

Seto, WH

Peiris, JSM

机构：

[1] Univ Hong Kong, Dept Microbiol, Hong Kong, Peoples R China

[2] Queen Mary Hosp, Dept Microbiol, Hong Kong, Peoples R China

[3] Johns Hopkins Univ, Sch Med, Dept Pharmacol & Mol Sci, Baltimore, MD 21205 USA

来源：

JOURNAL OF CLINICAL MICROBIOLOGY | 1998年 / 36卷 / 11期

关键词：

D O I：

10.1128/JCM.36.11.3359-3361.1998

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

A new immunoglobulin M (IgM) enzyme-linked immunosorbent assay (ELISA) based on the recombinant Epstein-Barr virus (EBV) matrix protein was developed. Compared to indirect immunofluorescence for the detection of IgM antibody to the EBV capsid antigen on clinical specimens, the sensitivity and specificity of the new IgM ELISA were 96 and 96%, respectively.

引用

页码：3359 / 3361

页数：3

共 11 条

[1]

CHAN KMA, UNPUB

[2] PROSPECTIVE EVALUATION OF HETEROPHILE AND EPSTEIN-BARR VIRUS-SPECIFIC IGM-ANTIBODY TESTS IN CLINICAL AND SUBCLINICAL INFECTIOUS-MONONUCLEOSIS - SPECIFICITY AND SENSITIVITY OF TESTS AND PERSISTENCE OF ANTIBODY [J].