Beneficial effects of Lactobacillus paracasei subsp paracasei NTU 101 and its fermented products

被引:133
作者
Chiang, Shen-Shih [2 ]
Pan, Tzu-Ming [1 ]
机构
[1] Natl Taiwan Univ, Coll Life Sci, Dept Biochem Sci & Technol, Taipei 10617, Taiwan
[2] Natl Chung Hsing Univ, Coll Agr & Nat Resources, Dept Food Sci & Biotechnol, Taichung 40227, Taiwan
关键词
Lactobacillus paracasei subsp; paracasei NTU 101; Hyperlipidemia; Hypertension; Gastric mucosal lesion; Osteoporosis; Obesity; LACTIC-ACID BACTERIA; ENTEROHEMORRHAGIC ESCHERICHIA-COLI; OVALBUMIN-SENSITIZED MICE; LONG-TERM INTERVENTION; BONE-MINERAL DENSITY; SOY-SKIM MILK; HELICOBACTER-PYLORI; IMMUNE-RESPONSE; BLOOD-PRESSURE; STRAIN;
D O I
10.1007/s00253-011-3753-x
中图分类号
Q81 [生物工程学(生物技术)]; Q93 [微生物学];
学科分类号
071005 [微生物学]; 090105 [作物生产系统与生态工程];
摘要
It is well-known that probiotics have a number of beneficial health effects in humans and animals, including the reduction of symptoms in lactose intolerance and enhancement of the bioavailability of nutrients. Probiotics have showed to possess antimutagenic, anticarcinogenic and hypocholesterolemic properties. Further, they were also observed to have antagonistic actions against intestinal and food-borne pathogens, to decrease the prevalence of allergies in susceptible individuals and to have immunomodulatory effects. Typically, the bacteria colonise the intestinal tract first and then reinforce the host defence systems by inducing a generalised mucosal immune response, balanced T-helper cell response, self-limited inflammatory response and secretion of polymeric IgA. Scientific reports showed that the Taiwan native lactic acid bacterium from newborn infant faeces identified as Lactobacillus paracasei subsp. paracasei NTU 101 and its fermented products proved to be effective for the management of blood cholesterol and pressure, prevention of gastric mucosal lesion development, immunomodulation and alleviation of allergies, anti-osteoporosis and inhibition the fat tissue accumulation. This review article describes that the beneficial effects of this Lactobacillus strains and derivative products may be suitable for human and animals.
引用
收藏
页码:903 / 916
页数:14
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