Small-angle neutron scattering studies of tubulin ring polymers

被引：5

作者：

Boukari, H. ^{[1
]}

Chernomordik, V. ^{[1
]}

Krueger, S. ^{[2
]}

Nossal, R. ^{[1
]}

Sackett, D. L. ^{[1
]}

机构：

[1] NIH, Bethesda, MD 20892 USA

[2] NIST, Gaithersburg, MD 20899 USA

来源：

PHYSICA B-CONDENSED MATTER | 2004年 / 350卷 / 1-3期

关键词：

Neutron scattering; Tubulin rings;

D O I：

10.1016/j.physb.2004.03.145

中图分类号：

O469 [凝聚态物理学];

学科分类号：

070205 ;

摘要：

We applied SANS to study nanoscale structures formed from tubulin and either of two similar peptides, cryptophycin1 and dolastatin10. A simple bead ring model adequately describes the cryptophycin-tubulin data, indicating high monodispersity and non-association of the rings. In contrast, dolastatin-tubulin samples show secondary assembly of larger structures. Analysis indicates that these macrostructures may contain locally stacked rings. (C) 2004 Elsevier B.V. All rights reserved.

引用

收藏

页码：E533 / E535

页数：3

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