Cyclin D1 and pancreatic carcinoma: A proliferative agonist and chemotherapeutic antagonist

被引：13

作者：

Diehl, JA ^{[1
]}

Benzeno, S ^{[1
]}

机构：

[1] Univ Penn, Leonard & Madlyn Abramson Family Canc Res Inst, Dept Canc Biol, Philadelphia, PA 19104 USA

来源：

CLINICAL CANCER RESEARCH | 2005年 / 11卷 / 16期

关键词：

D O I：

10.1158/1078-0432.CCR-05-1016

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

引用

页码：5665 / 5667

页数：3

共 20 条

[1] Phosphorylation-dependent regulation of cyclin D1 nuclear export and cyclin D1-dependent cellular transformation [J].

Alt, JR ;

Cleveland, JL ;

Hannink, M ;

Diehl, JA .

GENES & DEVELOPMENT, 2000, 14 (24) :3102-3114

[2] Overexpression of cyclin D1 promotes tumor cell growth and confers resistance to cisplatin-mediated apoptosis in an elastase-myc transgene-expressing pancreatic tumor cell line [J].

Biliran, H ;

Wang, Y ;

Banerjee, X ;

Xu, HM ;

Heng, H ;

Thakur, A ;

Bollig, A ;

Sarkar, FH ;

Liao, JD .

CLINICAL CANCER RESEARCH, 2005, 11 (16) :6075-6086

[3] Emerging roles for E2F: Beyond the G1/S transition and DNA replication [J].

Cam, H ;

Dynlacht, BD .

CANCER CELL, 2003, 3 (04) :311-316

[4] Glycogen synthase kinase 3β regulates cyclin D1 proteolysis and subcellular localization [J].

Diehl, JA ;

Cheng, MG ;

Roussel, MF ;

Sherr, CJ .

GENES & DEVELOPMENT, 1998, 12 (22) :3499-3511

[5]

Fry DW, 2004, MOL CANCER THER, V3, P1427

[6]

Guttridge DC, 1999, MOL CELL BIOL, V19, P5785

[7] The consensus motif for phosphorylation by cyclin D1-Cdk4 is different from that for phosphorylation by cyclin A/E-Cdk2 [J].

Kitagawa, M ;

Higashi, H ;

Jung, HK ;

SuzukiTakahashi, I ;

Ikeda, M ;

Tamai, K ;

Kato, J ;

Segawa, K ;

Yoshida, E ;

Nishimura, S ;

Taya, Y .

EMBO JOURNAL, 1996, 15 (24) :7060-7069

[8]

Korc M, 1998, Surg Oncol Clin N Am, V7, P25

[9]

Kornmann M, 1999, CANCER RES, V59, P3505

[10] Inhibition of basal and mitogen-stimulated pancreatic cancer cell growth by cyclin D1 antisense is associated with loss of tumorigenicity and potentiation of cytotoxicity to cisplatinum [J].

Kornmann, M ;

Arber, N ;

Korc, M .

JOURNAL OF CLINICAL INVESTIGATION, 1998, 101 (02) :344-352

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