High seroprevalence of human metapneumovirus among young children in Israel

被引：80

作者：

Wolf, DG

Zakay-Rones, Z

Fadeela, A

Greenberg, D

Dagan, R

机构：

[1] Hadassah Univ Hosp & Med Sch, Dept Clin Microbiol & Infect Dis, IL-91120 Jerusalem, Israel

[2] Hadassah Univ Hosp & Med Sch, Dept Virol, IL-91120 Jerusalem, Israel

[3] Soroka Univ, Med Ctr, Pediat Infect Dis Unit, Beer Sheva, Israel

[4] Ben Gurion Univ Negev, Fac Hlth Sci, Beer Sheva, Israel

来源：

JOURNAL OF INFECTIOUS DISEASES | 2003年 / 188卷 / 12期

关键词：

D O I：

10.1086/380100

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Exposure to the newly discovered human metapneumovirus (HMPV) during the first 2 years of life was studied by longitudinal serological analysis in 40 healthy children in southern Israel. The seropositivity rate decreased to a minimum by age 13 months and increased to 52% by age 24 months. Evidence of new infection was detected in 13%, 23%, and 55% of children by ages 7, 13, and 24 months, respectively. The high exposure rates suggest that HMPV may be an important cause of community-acquired respiratory-tract infections in young children.

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页码：1865 / 1867

页数：3

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