Fluorine-containing α-alkynyl amino esters and access to a new family of 3,4-dehydroproline analogues

被引：66

作者：

Sémeril, D

Le Nôtre, J

Bruneau, C

Dixneuf, PH

Kolomiets, AF

Osipov, SN

机构：

[1] Univ Rennes, CNRS, UMR 6509, Lab Organomet & Catalyse Chim & Elctrochim Mol, F-35042 Rennes, France

[2] Russian Acad Sci, AN Nesmeyanov Organoelement Cpds Inst, Moscow 117813, Russia

来源：

NEW JOURNAL OF CHEMISTRY | 2001年 / 25卷 / 01期

关键词：

D O I：

10.1039/b007396m

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

New alpha -alkynyl, alpha -CF(3) amino esters have been prepared from electrophilic imines and used to produce 3-alkenyl-3,4-dehydroproline derivatives, via enyne metathesis with the precatalyst [Ru=C=C=CPh(2)(Cl)(PCy(3))(arene)]O(3)SCF(3). These new conjugated fluorine-containing dienes are active substrates for the Diels-Alder reaction and lead to a new class of bicyclic amino esters.

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页码：16 / 18

页数：3

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