A note on confidence intervals in cost-effectiveness analysis

被引:109
作者
Tambour, M [1 ]
Zethraeus, N [1 ]
Johannesson, M [1 ]
机构
[1] Stockholm Sch Econ, S-11383 Stockholm, Sweden
关键词
D O I
10.1017/S0266462300011442
中图分类号
R19 [保健组织与事业(卫生事业管理)];
学科分类号
摘要
How to obtain confidence intervals for cost-effectiveness ratios is complicated by the statistical problems of obtaining a confidence interval for a ratio of random variables, Different approaches have been suggested in the literature, but no consensus has been reached, We propose an alternative simple solution to this problem. By multiplying the effectiveness units by the price per effectiveness unit, both costs and benefits can be expressed in monetary terms and standard statistical techniques can be used to estimate a confidence interval for net benefits, This approach avoids the ratio estimation problem and explicitly recognizes that the price per effectiveness unit has to be known to provide cost-effectiveness analysis with a useful decision rule.
引用
收藏
页码:467 / 471
页数:5
相关论文
共 11 条
  • [1] Chaudhary MA, 1996, STAT MED, V15, P1447
  • [2] Drummond M, 1993, Health Econ, V2, P205, DOI 10.1002/hec.4730020303
  • [3] Efron B., 1993, MONOGR STAT APPL PRO, V57
  • [4] Johannesson M, 1996, THEORY METHODS EC EV
  • [5] Newbold P., 1991, STAT BUSINESS EC
  • [6] Bootstrap analyses of cost effectiveness in antidepressant pharmacotherapy
    Obenchain, RL
    Melfi, CA
    Croghan, TW
    Buesching, DP
    [J]. PHARMACOECONOMICS, 1997, 11 (05) : 464 - 472
  • [7] IN SEARCH OF POWER AND SIGNIFICANCE - ISSUES IN THE DESIGN AND ANALYSIS OF STOCHASTIC COST-EFFECTIVENESS STUDIES IN HEALTH-CARE
    OBRIEN, BJ
    DRUMMOND, MF
    LABELLE, RJ
    WILLAN, A
    [J]. MEDICAL CARE, 1994, 32 (02) : 150 - 163
  • [8] Phelps C E, 1991, Int J Technol Assess Health Care, V7, P12
  • [9] CONFIDENCE-INTERVALS FOR COST/EFFECTIVENESS RATIOS
    WAKKER, P
    KLAASSEN, MP
    [J]. HEALTH ECONOMICS, 1995, 4 (05) : 373 - 381
  • [10] Weinstein M, 1973, J PUBLIC ECON, V2, P147, DOI [DOI 10.1016/0047-2727(73)90002-9, 10.1016/0047-2727(73)90002-9]