Multicenter evaluation of a Candida albicans peptide nucleic acid fluorescent in situ hybridization probe for characterization of yeast isolates from blood cultures

被引:66
作者
Wilson, DA
Joyce, MJ
Hall, LS
Reller, LB
Roberts, GD
Hall, GS
Alexander, BD
Procop, GW
机构
[1] Cleveland Clin Fdn, Clin Microbiol Sect, Cleveland, OH 44195 USA
[2] Duke Univ, Ctr Med, Clin Microbiol Lab, Durham, NC USA
[3] Mayo Clin, Div Clin Microbiol, Rochester, MN USA
关键词
D O I
10.1128/JCM.43.6.2909-2912.2005
中图分类号
Q93 [微生物学];
学科分类号
071005 ; 100705 ;
摘要
We evaluated aliquots from 244 clinical blood culture bottles that demonstrated yeasts on Gram stain using a Candida albicans peptide nucleic acid (PNA) fluorescent in situ hybridization (FISH) probe. The sensitivity, specificity, positive predictive value, and negative predictive value of the C albicans PNA FISH test in this study were 99%, 100%, 100%, and 99.3%, respectively.
引用
收藏
页码:2909 / 2912
页数:4
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