Posttransplant microbiological surveillance

被引:15
作者
Snydman, DR
机构
[1] Tufts Univ New England Med Ctr, Dept Med, NEMC 238, Boston, MA 02111 USA
[2] Tufts Univ New England Med Ctr, Dept Pathol, Boston, MA 02111 USA
[3] Tufts Univ, Sch Med, Boston, MA 02111 USA
关键词
D O I
10.1086/320900
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
Posttransplant microbiological surveillance should be used when the likelihood of infection in a transplant recipient is high and the sensitivity and specificity of the test can provide a high positive or negative predictive value. Testing is also performed in some instances to monitor the patient's response to therapy. Examples of successful posttransplant microbiological surveillance include molecular detection of cytomegalovirus and Epstein-Barr virus and virus load determinations, as well as hepatitis B and C detection and virus load testing. Routine fungal and bacterial surveillance are generally not necessary, except for Candida colonization detection or vancomycin-resistant enterococcal detection in high-risk subgroups. The organ transplanted may also play a role in the type of routine surveillance recommended.
引用
收藏
页码:S22 / S25
页数:4
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