Characterization of acute myeloid leukemia with PTPN11 mutation:: the mutation is closely associated with NPM1 mutation but inversely related to FLT3/ITD

被引：58

作者：

Hou, H-A ^{[1
,2
]}

Chou, W-C ^{[3
]}

Lin, L-I ^{[4
]}

Chen, C-Y ^{[2
]}

Tang, J-L ^{[2
]}

Tseng, M-H ^{[2
]}

Huang, C-F ^{[2
]}

Chiou, R-J ^{[2
]}

Lee, F-Y ^{[3
]}

Liu, M-C ^{[3
]}

Tien, H-F ^{[2
]}

机构：

[1] Natl Taiwan Univ, Natl Taiwan Univ Hosp, YunLin Branch, Coll Med,Dept Internal Med,Div Hematol, Touliu, Taiwan

[2] Natl Taiwan Univ, Natl Taiwan Univ Hosp, Coll Med,Dept Internal Med,Div Hematol, Taipei, Taiwan

[3] Natl Taiwan Univ, Natl Taiwan Univ Hosp, Dept Lab Med, Touliu, Taiwan

[4] Natl Taiwan Univ, Coll Med, Dept Cin Lab Sci & Med Biotechnol, Taipei 10764, Taiwan

来源：

LEUKEMIA | 2008年 / 22卷 / 05期

关键词：

D O I：

10.1038/sj.leu.2405005

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

引用

页码：1075 / 1078

页数：4

共 7 条

[1] Acquisition of JAK2, PTPN11, and RAS mutations during disease progression in primary myelodysplastic syndrome [J].

Chen, C-Y ;

Lin, L-I ;

Tang, J-L ;

Tsay, W. ;

Chang, H-H ;

Yeh, Y-C ;

Huang, C-F ;

Chiou, R-J ;

Yao, M. ;

Ko, B-S ;

Chen, Y-C ;

Lin, K-H ;

Lin, D-T ;

Tien, H-F .

LEUKEMIA, 2006, 20 (06) :1155-1158

[2] RUNX1 gene mutation in primary myelodysplastic syndrome -: the mutation can be detected early at diagnosis or acquired during disease progression and is associated with poor outcome [J].

Chen, Chien-Yuan ;

Lin, Liang-In ;

Tang, Jih-Luh ;

Ko, Bo-Sheng ;

Tsay, Woei ;

Chou, Wen-Chien ;

Yao, Ming ;

Wu, Shang-Ju ;

Tseng, Mei-Hsuan ;

Tien, Hwei-Fang .

BRITISH JOURNAL OF HAEMATOLOGY, 2007, 139 (03) :405-414

[3] Nucleophosmin mutations in De novo acute myeloid leukemia:: The age-dependent incidences and the stability during disease [J].

Chou, WC ;

Tang, JL ;

Lin, LI ;

Yao, M ;

Tsay, W ;

Chen, CY ;

Wu, SJ ;

Huang, CF ;

Chiou, RJ ;

Tseng, MH ;

Lin, DT ;

Lin, KH ;

Chen, YC ;

Tien, HF .

CANCER RESEARCH, 2006, 66 (06) :3310-3316

[4] Genetics of myeloid malignancies:: Pathogenetic and clinical implications [J].

Fröhling, S ;

Scholl, C ;

Gilliland, DG ;

Levine, RL .

JOURNAL OF CLINICAL ONCOLOGY, 2005, 23 (26) :6285-6295

[5] Genetic's of myeloid leukemias [J].

Kelly, LM ;

Gilliland, DG .

ANNUAL REVIEW OF GENOMICS AND HUMAN GENETICS, 2002, 3 :179-198

[6] Diversity and functional consequences of germline and somatic PTPN11 mutations in human disease [J].

Tartaglia, M ;

Martinelli, S ;

Stella, L ;

Bocchinfuso, G ;

Flex, E ;

Cordeddu, V ;

Zampino, G ;

van der Burgt, I ;

Palleschi, A ;

Petrucci, TC ;

Sorcini, M ;

Schoch, C ;

Foà, R ;

Emanuel, PD ;

Gelb, BD .

AMERICAN JOURNAL OF HUMAN GENETICS, 2006, 78 (02) :279-290

[7] Mutations in PTPN11, encoding the protein tyrosine phosphatase SHP-2, cause Noonan syndrome [J].

Tartaglia, M ;

Mehler, EL ;

Goldberg, R ;

Zampino, G ;

Brunner, HG ;

Kremer, H ;

van der Burgt, I ;

Crosby, AH ;

Ion, A ;

Jeffery, S ;

Kalidas, K ;

Patton, MA ;

Kucherlapati, RS ;

Gelb, BD .

NATURE GENETICS, 2001, 29 (04) :465-468

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