Are antineutrophil cytoplasmic antibody-associated vasculitides pauci-immune?

被引：30

作者：

Brons, RH

Kallenberg, CGM

Tervaert, JWC

机构：

[1] Univ Groningen Hosp, Dept Clin Immunol, NL-9713 GZ Groningen, Netherlands

[2] Univ Hosp Maastricht, Dept Clin & Expt Immunol, Maastricht, Netherlands

来源：

RHEUMATIC DISEASE CLINICS OF NORTH AMERICA | 2001年 / 27卷 / 04期

关键词：

D O I：

10.1016/S0889-857X(05)70238-6

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

The role of immune complexes in antineutrophil cytoplasmic antibody (ANCA)-associated vasculitides remains controversial. The ANCA-associated vasculitides are described as being pauci-immune. The authors hypothesize that the absence of immune complexes is a result of an exaggerated inflammatory response due to the presence of ANCA. The authors present evidence indicating that immune complexes may play a role in the initiation or relapses of the disease.

引用

页码：833 / +

页数：17

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