A review of near infrared spectroscopy and chemometrics in pharmaceutical technologies

被引：1099

作者：

Roggo, Yves ^{[1
]}

Chalus, Pascal ^{[1
]}

Maurer, Lene ^{[1
]}

Lema-Martinez, Carmen ^{[1
]}

Edmond, Aurelie ^{[1
]}

Jent, Nadine ^{[1
]}

机构：

[1] F Hoffmann La Roche & Co Ltd, CH-4002 Basel, Switzerland

来源：

JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS | 2007年 / 44卷 / 03期

关键词：

near infrared spectroscopy; chemometrics; pharmaceuticals; on-line; quality control; identification; qualification; quantification;

D O I：

10.1016/j.jpba.2007.03.023

中图分类号：

O65 [分析化学];

学科分类号：

070302 [分析化学]; 081704 [应用化学];

摘要：

Near-infrared spectroscopy (NIRS) is a fast and non-destructive analytical method. Associated with chemometrics, it becomes a powerful tool for the pharmaceutical industry. Indeed, NIRS is suitable for analysis of solid, liquid and biotechnological pharmaceutical forms. Moreover, NIRS can be implemented during pharmaceutical development, in production for process monitoring or in quality control laboratories. This review focuses on chemometric techniques and pharmaceutical NIRS applications. The following topics are covered: qualitative analyses, quantitative methods and on-line applications. Theoretical and practical aspects are described with pharmaceutical examples of NIRS applications. (c) 2007 Elsevier B.V. All rights reserved.

引用

页码：683 / 700

页数：18

共 243 条

[1]

Adams MJ., 1995, CHEMOMETRICS ANAL SP

[2]

Quantitative analysis of film coating in a fluidized bed process by in line NIR spectrometry and multivariate batch calibration [J].

Andersson, M ;

Folestad, S ;

Gottfries, J ;

Johansson, MO ;

Josefson, M ;

Wahlund, KG .

ANALYTICAL CHEMISTRY, 2000, 72 (09) :2099-2108

[3]

Monitoring of a film coating process for tablets using near infrared reflectance spectrometry [J].

Andersson, M ;

Josefson, M ;

Langkilde, FW ;

Wahlund, KG .

JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 1999, 20 (1-2) :27-37

[4]

Multivariate analysis and classification of the chemical quality of 7-aminocephalosporanic acid using near-infrared reflectance spectroscopy [J].

Andre, M .

ANALYTICAL CHEMISTRY, 2003, 75 (14) :3460-3467

[5]

[Anonymous], CHEMOMETR INTELL LAB, DOI DOI 10.1016/S0169-7439(02)00085-0

[6]

At-line monitoring of a submerged filamentous bacterial cultivation using near-infrared spectroscopy [J].

Arnold, SA ;

Crowley, J ;

Vaidyanathan, S ;

Matheson, L ;

Mohan, P ;

Hall, JW ;

Harvey, LM ;

McNeil, B .

ENZYME AND MICROBIAL TECHNOLOGY, 2000, 27 (09) :691-697

[7]

In-situ near infrared spectroscopy to monitor key analytes in mammalian cell cultivation [J].

Arnold, SA ;

Crowley, J ;

Woods, N ;

Harvey, LM ;

McNeill, B .

BIOTECHNOLOGY AND BIOENGINEERING, 2003, 84 (01) :13-19

[8]

ARNOLD SA, 2003, BIOPHARM INT JAN

[9]

ARNOLD SA, 2002, BIOPHARM INTERN NOV

[10]

Effects of transforming growth factor-β deficiency on bone development:: A Fourier transform-infrared imaging analysis [J].

Atti, E ;

Gomez, S ;

Wahl, SM ;

Mendelsohn, R ;

Paschalis, E ;

Boskey, AL .

BONE, 2002, 31 (06) :675-684

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