Single lipid diffusion in Langmuir monolayers

被引:35
作者
Forstner, MB
Käs, J
Martin, D [1 ]
机构
[1] Univ Texas, Dept Phys, Ctr Nonlinear Dynam, Austin, TX 78705 USA
[2] Univ Texas, Inst Mol & Cellular Biol, Ctr Nonlinear Dynam, Austin, TX 78705 USA
[3] Univ Texas, Ctr Nano & Mol Sci & Technol, Austin, TX 78705 USA
[4] Univ Texas, Texas Mat Inst, Austin, TX 78705 USA
关键词
D O I
10.1021/la000795n
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
Individual lipid movement in a monolayer is studied over long time intervals (500 s) by darkfield microscopy of single lipids labeled with gold colloids (30 or 100 nm in diameter). Dimyristoyl phosphatidylcholine in the fluid phase shows normal diffusion, with a diffusion coefficient of (1.1 +/- 0.2) x 10(-8) cm(2)/s. Since this is consistent with values derived from the diffusive transport of many Lipids, the analysis of gold-tagged lipids in a monolayer provides a reliable picture of lipid diffusion on the level of single molecules.
引用
收藏
页码:567 / 570
页数:4
相关论文
共 24 条