Cathodic adsorptive stripping voltammetric determination of muscle relaxant: gallamine triethiodide (flaxedil)

被引：9

作者：

Ali, AMM ^{[1
]}

Ghandour, MA

Abd-El-Fattah, MM

机构：

[1] Assiut Univ, Fac Sci, Dept Chem, Assiut 71516, Egypt

[2] Zagazig Univ, Fac Sci, Dept Chem, Zagazig, Egypt

来源：

JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS | 2001年 / 25卷 / 01期

关键词：

flaxedil (gallamine triethiodide); cathodic linear sweep; adsorptive stripping voltammetry; flaxedil ampoule;

D O I：

10.1016/S0731-7085(00)00439-8

中图分类号：

O65 [分析化学];

学科分类号：

070302 ; 081704 ;

摘要：

A senstive and simple voltammetric method of analysis is developed for the determination of trace amounts of gallamine triethiode in phosphate media. This method is based on controlled adsorptive preconcentration of the relaxant onto a Hanging Mercury Drop Electrode (HMDE) whereby mercurous iodide salt(s) are formed. The technique used is Cathodic Linear Sweep Stripping Voltammetry (CLSSV). The adsorptive response was evaluated with respect to preconcentration time and potential. As little as 3 x 10(-9) mol dm(-3) i.e. 2.7 ppb flaxedil (proconcentration time 300 seconds) can be determined successfully. The application of this method was tested in the determination of flaxedil in pharmaceutical preparation (ampoules). (C) 2001 Elsevier Science B.V. All rights reserved.

引用

页码：31 / 37

页数：7

共 22 条

[1] ION-SELECTIVE MEMBRANE ELECTRODES FOR THE DETERMINATION OF THE MUSCLE-RELAXANTS PANCURONIUM, TUBOCURARINE, GALLAMINE AND SUCCINYLCHOLINE [J].