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Generating diversity at GABAergic synapses

被引：192
作者：
Cherubini, E [1 ]
Conti, F
机构：
[1] Scuola Int Super Studi Avanzati, Ist Nazl Fis, Mat Unit, Biophys Sector, I-34014 Trieste, Italy
[2] Univ Ancona, Ist Fisiol Umana, I-60020 Ancona, Italy
来源：
TRENDS IN NEUROSCIENCES | 2001年 / 24卷 / 03期
关键词：
D O I：
10.1016/S0166-2236(00)01724-0
中图分类号：
Q189 [神经科学];
学科分类号：
071006 ;
摘要：
GABA-mediated transmission is characterized by high variability of synaptic responses. Major contributors to this variability are: presynaptic factors. including release probability and number of release sites; factors that determine synaptic GABA transients in the cleft, including diffusion and the actions of GABA transporters; and postsynaptic factors, including GABA, receptors subtypes, their location and number, their modulation by endogenous and exogenous factors, and their interactions with postsynaptic-anchoring proteins.
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页码：155 / 162
页数：8
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