Dairy Consumption and the Incidence of Hyperglycemia and the Metabolic Syndrome Results from a French prospective study, Data from the Epidemiological Study on the Insulin Resistance Syndrome (DESIR)

被引:133
作者
Fumeron, Frederic [1 ,2 ]
Lamri, Amel [1 ,2 ]
Khalil, Charbel Abi [1 ,3 ]
Jaziri, Riphed [1 ,2 ]
Porchay-Balderelli, Isabelle [1 ,2 ]
Lantieri, Olivier [4 ]
Vol, Sylviane [4 ]
Balkau, Beverley [5 ,6 ]
Marre, Michel [1 ,2 ,3 ]
机构
[1] INSERM, U695, Paris, France
[2] Univ Paris 07, UFR Med Site Bichat, Paris, France
[3] Bichat Claude Bernard Hosp, AP HP, Dept Endocrinol Diabetol Nutr & Metab Dis, Paris, France
[4] Inst Inter Reg Sante, Irsa, La Riche, France
[5] INSERM, CESP Ctr Res Epidemiol & Populat Hlth, U1018, Epidemiol Diabet Obes & Chron Kidney Dis Lifecour, Villejuif, France
[6] Univ Paris 11, Unite Mixte Rech Sante 1018, Villejuif, France
关键词
MILK-FAT; MYOCARDIAL-INFARCTION; RISK-FACTORS; BODY-WEIGHT; PRODUCTS; CALCIUM; MEN;
D O I
10.2337/dc10-1772
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
OBJECTIVE-In the French Data from the Epidemiological Study on the Insulin Resistance Syndrome (DESIR) cohort, cross-sectional analyses have shown that a higher consumption of dairy products and calcium are associated with a lower prevalence of the metabolic syndrome (MetS). We assess the influence of dairy products on 9-year incident MetS and on impaired fasting glycemia and/or type 2 diabetes (IFG/T2D). RESEARCH DESIGN AND METHODS-Men and women who completed a food frequency questionnaire at baseline and after 3 years were studied (n = 3,435). Logistic regression models were used to study associations between the average year 0 and year 3 consumption of milk and dairy products, cheese, dietary calcium density, and incident MetS and IFG/T2D after adjusting for 1) sex, age, alcohol, smoking, physical activity, fat intake and 2) additionally for BMI. Associations between dairy products and continuous variables were studied by repeated-measures ANCOVA, using the same covariates. RESULTS-Dairy products other than cheese, and dietary calcium density, were inversely associated with incident MetS and IFG/T2D, cheese was negatively associated with incident MetS. All three parameters were associated with lower diastolic blood pressure, and with a lower EM! gain. Higher cheese intake and calcium density were associated with a lower increase in waist circumference and lower triglyceride levels. Calcium density was also associated with a lower systolic blood pressure and a lower 9-year increase in plasma triglyceride levels. CONCLUSIONS-A higher consumption of dairy products and calcium was associated with a lower 9-year incidence of MetS and IFG/T2D in a large cohort drawn from the general population. Diabetes Care 34:813-817, 2011
引用
收藏
页码:813 / 817
页数:5
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