Separation of blood in microchannel bends

被引：12

作者：

Blattert, C ^{[1
]}

Jurischka, R ^{[1
]}

Schoth, A ^{[1
]}

Kerth, P ^{[1
]}

Menz, W ^{[1
]}

机构：

[1] Univ Freiburg, Inst Mikrosyst Tech, Freiburg, Germany

来源：

MICROFLUIDICS, BIOMEMS, AND MEDICAL MICROSYSTEMS II | 2004年 / 5345卷

关键词：

bend; blood; disposable; hot embossing; microchannel; microfluidic; separation; UV-LIGA; rapid prototyping; rapid processing;

D O I：

10.1117/12.522780

中图分类号：

TM [电工技术]; TN [电子技术、通信技术];

学科分类号：

0808 ; 0809 ;

摘要：

Biological applications of micro assay devices require integrated on-chip microfluidics for separation of plasma or serum from blood. This is achieved by a new blood separation technique based on a microchannel bend structure developed within the collaborative Micro-Tele-BioChip (muTBC) project co-funded by the German Ministry For Education and Research (BMBF). Different prototype polymer chips have been manufactured with an UV-LIGA process and hot embossing technology. The separation efficiency of these chips has been determined by experimental measurements using human whole blood. Results show different separation efficiencies for cells and plasma depending on microchannel geometry and blood sample characteristics and suggest an alternative blood separation method as compared to existing micro separation technologies.

引用

页码：17 / 25

页数：9

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