Codon usage in Plasmodium vivax nuclear genes

被引：8

作者：

Chen, NN ^{[1
]}

Cheng, Q ^{[1
]}

机构：

[1] Australian Army Malaria Inst, Dept Parasitol, Brisbane, Qld 4052, Australia

来源：

INTERNATIONAL JOURNAL FOR PARASITOLOGY | 1999年 / 29卷 / 03期

关键词：

amino-acid composition; codon usage; Plasmodium falciparum; Plasmodium vivax;

D O I：

10.1016/S0020-7519(98)00211-2

中图分类号：

R38 [医学寄生虫学]; Q [生物科学];

学科分类号：

07 ; 0710 ; 09 ; 100103 ;

摘要：

Codon usage in Plasmodium vivax nuclear genes was analysed and compared with that in Plasmodium falciparum nuclear genes. Preferred codons were determined for P. vivax. Unlike P. falciparum, P. vivax genes are about 15% less A + T rich in the coding regions, with no obvious AST bias at the third position of the codons. The amino-acid composition of P. vivax gene products is also different from that of P. falciparum. These results provide valuable information to facilitate gene cloning as well as expression and transfection studies for P. vivax. (C) 1999 Australian Society for Parasitology. Published by Elsevier Science Ltd. All rights reserved.

引用

页码：445 / 449

页数：5

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