Pulmonary toxicity of 1-D nanocarbon materials

被引:41
作者
Huczko, A
Lange, H
Bystrzejewski, M
Baranowski, P
Grubek-Jaworska, H
Nejman, P
Przybylowski, T
Czuminska, K
Glapinski, J
Walton, DRM
Kroto, HW
机构
[1] Warsaw Univ, Dept Chem, PL-02093 Warsaw, Poland
[2] Med Univ Warsaw, Dept Pneumol, Warsaw, Poland
[3] Agr Univ Warsaw, Fac Vet Med, Warsaw, Poland
[4] PAS, Inst Biocybernet & Biomed Engn, Warsaw, Poland
[5] Univ Sussex, Sch Life Sci, Brighton, E Sussex, England
关键词
1-D nanocarbon materials; health hazard; long toxicity and pathogenicity; guinea pigs;
D O I
10.1081/FST-200050691
中图分类号
O64 [物理化学(理论化学)、化学物理学];
学科分类号
070304 ; 081704 ;
摘要
1-D (one-dimensional) nanocarbon materials possess unique properties. However, they could become airborne and reach the lungs. In the present study the pulmonary toxicity of nanotubes was investigated. Guinea pigs were intratracheally instilled with different nanotubes and inflammatory response was measured. The results show that both the duration of exposure and material characteristics can affect the respiratory process and induce pathological reaction in lung tissue.
引用
收藏
页码:141 / 145
页数:5
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