Fresh-frozen plasma transfusion strategy in trauma with massive and ongoing bleeding. Common (sense) and sensibility

被引:15
作者
Ho, Anthony M. -H. [1 ]
Dion, Peter W. [2 ]
Yeung, Janice H. H. [3 ]
Ng, Calvin S. H. [4 ]
Karmakar, Manoj K. [1 ]
Critchley, Lester A. H. [1 ]
Rainer, Timothy H. [3 ]
Cheung, Chi Wai [5 ]
Tay, Beng A. [1 ]
机构
[1] Chinese Univ Hong Kong, Prince Wales Hosp, Dept Anaesthesia & Intens Care, Shatin, Hong Kong, Peoples R China
[2] Sr Catharines Gen Hosp, Dept Anaesthesia, St Catharines, ON, Canada
[3] Chinese Univ Hong Kong, Prince Wales Hosp, Dept Accid & Emergency Med, Shatin, Hong Kong, Peoples R China
[4] Chinese Univ Hong Kong, Prince Wales Hosp, Dept Surg, Shatin, Hong Kong, Peoples R China
[5] Univ Hong Kong, Dept Anaesthesiol, Hong Kong, Hong Kong, Peoples R China
关键词
Coagulopathy; Fresh-frozen plasma; Red blood cells; Transfusion; Trauma; RED-BLOOD-CELL; ORGAN FAILURE; WHOLE-BLOOD; MORTALITY; RATIO; COAGULOPATHY; COAGULATION; PLATELETS; SURVIVAL; OUTCOMES;
D O I
10.1016/j.resuscitation.2010.02.030
中图分类号
R4 [临床医学];
学科分类号
1002 ; 100602 ;
摘要
During trauma resuscitation involving massive transfusion, the best fresh-frozen plasma to packed red blood cells ratio is unknown. No randomised controlled trial (RCT) is available on this subject, although there are plenty of observational studies suggesting that the ratio should be about 1:1. This ratio also makes more physiological sense, and we suggest that in patients with massive and ongoing bleeding, it is a sensible strategy with which to start resuscitation. (C) 2010 Elsevier Ireland Ltd. All rights reserved.
引用
收藏
页码:1079 / 1081
页数:3
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