Bioactive constituents of Chinese natural medicines. VI. Moutan cortex. (2): Structures and radical scavenging effects of suffruticosides A, B, C, D, and E and galloyl-oxypaeoniflorin

被引:56
作者
Matsuda, H [1 ]
Ohta, T [1 ]
Kawaguchi, A [1 ]
Yoshikawa, M [1 ]
机构
[1] Kyoto Pharmaceut Univ, Yamashima Ku, Kyoto 6078412, Japan
关键词
Paeonia suffruticosa; suffruticoside; galloyl-oxypaeoniflorin; radical scavenging effect; Moutan Cortex;
D O I
10.1248/cpb.49.69
中图分类号
R914 [药物化学];
学科分类号
100701 ;
摘要
Five paeonol glycosides, suffruticosides A, B, C, D, and E, and a monoterpene glucoside, galloyl-oxypaeoniflorin, were isolated from the glycosidic fraction of Chinese Moutan Cortex, the root cortex of Paeonia suffruticosa ANDREWS, together with paeonolide, apiopaeonoside, galloyl-paeoniflorin, oxypaeoniflorin, and paeoniflorin. The structures of five suffruticosides and galloyl-oxypaeoniflorin were elucidated on the basis of chemical and physicochemical evidence. Suffruticosides A, B, C, and D, galloyl-oxypaeoniflorin, and galloyl-paeoniflorin exhibited more potent radical scavenging effects than alpha -tocopherol.
引用
收藏
页码:69 / 72
页数:4
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