Ruthenium-catalyzed polycyclization reactions

被引：83

作者：

Zuercher, WJ ^{[1
]}

Scholl, M ^{[1
]}

Grubbs, RH ^{[1
]}

机构：

[1] CALTECH, Div Chem & Chem Engn, Arnold & Mabel Beckman Labs Chem Synthesis, Pasadena, CA 91125 USA

来源：

JOURNAL OF ORGANIC CHEMISTRY | 1998年 / 63卷 / 13期

关键词：

D O I：

10.1021/jo972279g

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The application of ruthenium alkylidenes such as 1 to the catalysis of polycyclization reactions is reported. Several acyclic precursors have been synthesized and reacted with 1. These precursors vary in topology and contain acetylenic and/or cycloolefinic metathesis relays. The cyclization reactions proceed in moderate to good yields to produce polycyclic polyenes when the precursors are subjected to catalytic amounts of 1. In general, precursors bearing n relay units generate polycycles containing (n + 1) rings.

引用

页码：4291 / 4298

页数：8

共 31 条

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