Pregnancy and Pulmonary Hypertension

被引:23
作者
Lane, C. Randall [1 ]
Trow, Terence K. [1 ]
机构
[1] Yale Univ, Sch Med, Pulm & Crit Care Med Sect, Yale Pulm Hypertens Ctr, New Haven, CT 06520 USA
关键词
Pulmonary hypertension; Pregnancy; Management; Conception counseling; INHALED NITRIC-OXIDE; BONE-MINERAL DENSITY; EISENMENGER-SYNDROME; VASCULAR-DISEASE; HEART-DISEASE; EPOPROSTENOL; MANAGEMENT; SILDENAFIL; HEPARIN; WOMEN;
D O I
10.1016/j.ccm.2010.10.006
中图分类号
R56 [呼吸系及胸部疾病];
学科分类号
摘要
When pulmonary hypertension (PH) occurs in pregnancy, physiologic stress can overwhelm an already strained right ventricle resulting in right ventricular failure and death. Mortality remains unacceptably high (25%-30%). Patients with PH should be counseled to avoid pregnancy. This article discusses the physiologic changes of pregnancy that make it difficult for patients with PH, the pitfalls of transthoracic echocardiography in diagnosing PH in pregnancy, and the historical data regarding mortality. The causes of development of PH during pregnancy are discussed, and the limited data on management of patients with PH who choose to carry their pregnancy to term are reviewed.
引用
收藏
页码:165 / +
页数:11
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