Induction of protein secretory pathway is required for systemic acquired resistance

被引：435

作者：

Wang, D ^{[1
]}

Weaver, ND ^{[1
]}

Kesarwani, M ^{[1
]}

Dong, XN ^{[1
]}

机构：

[1] Duke Univ, Dept Biol, Dev Cell & Mol Biol Grp, Durham, NC 27708 USA

来源：

SCIENCE | 2005年 / 308卷 / 5724期

关键词：

D O I：

10.1126/science.1108791

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

In plants, systemic acquired resistance (SAR) is established as a result of NPR1-regulated expression of pathogenesis-related (PR) genes. Using gene expression profiling in Arabidopsis, we found that in addition to controlling the expression of PR genes, NPR1 also directly controls the expression of the protein secretory pathway genes. Up-regulation of these genes is essential for SAR, because mutations in some of them diminished the secretion of PR proteins (for example, PR1), resulting in reduced resistance. We provide evidence that NPR1 coordinately,regulates these secretion-related genes through a previously undescribed cis-element. Activation of this cis-element is controlled by a transcription factor that is translocated into the nucleus upon SAR induction.

引用

页码：1036 / 1040

页数：5

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