Bariatric surgery for diabetes management

被引:17
作者
Frachetti, Katherine J. [1 ,3 ]
Goldfine, Allison B. [1 ,2 ]
机构
[1] Harvard Univ, Sch Med, Boston, MA 02215 USA
[2] Joslin Diabet Ctr, Boston, MA 02215 USA
[3] Beth Israel Deaconess Med Ctr, Boston, MA 02215 USA
关键词
bariatric surgery; obesity; type 2 diabetes mellitus; Y GASTRIC BYPASS; GLUCAGON-LIKE PEPTIDE-1; LONG-TERM MORTALITY; WEIGHT-LOSS; PLASMA GHRELIN; LIFE-STYLE; HYPOGLYCEMIA; OBESITY; DIET; DEFICIENCY;
D O I
10.1097/MED.0b013e32832912e7
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Purpose of review To review the role of bariatric surgery in the treatment of patients with type 2 diabetes. Recent findings Multiple studies demonstrate that bariatric surgical approaches to obesity lead to substantial and sustained weight loss. Patients with diabetes have remission of hyperglycemia or require reduced medications. Surgical intervention for patients with more recent diabetes onset may have higher rates of resolution than patients with longer duration disease. In addition, dyslipidemia and hypertension improve. A short-term randomized clinical trial comparing laproscopic banding with optimal medical management suggests surgery leads to more improvement in multiple metabolic measures. Perioperative risk is low and observational studies suggest long-term survival is favorable for obese patients following bariatric surgery. Metabolic risks of bariatric procedures are reviewed. Summary Although there are several surgical approaches for weight management, improvements in diabetes, including achievement of near normal glycemia without medication or reduced medications, are realized in many patients. Early surgical intervention for overweight type 2 diabetes may be clinically appropriate in patients for in whom operative risks are acceptable.
引用
收藏
页码:119 / 124
页数:6
相关论文
共 41 条
[1]   Long-term mortality after gastric bypass surgery [J].
Adams, Ted D. ;
Gress, Richard E. ;
Smith, Sherman C. ;
Halverson, R. Chad ;
Simper, Steven C. ;
Rosamond, Wayne D. ;
LaMonte, Michael J. ;
Stroup, Antoinette M. ;
Hunt, Steven C. .
NEW ENGLAND JOURNAL OF MEDICINE, 2007, 357 (08) :753-761
[2]  
[Anonymous], 2000, Arch Intern Med, V160, P898
[3]   Progressive rise in gut hormone levels after Roux-en-Y gastric bypass suggests gut adaptation and explains altered satiety [J].
Borg, CM ;
le Roux, CW ;
Ghatei, MA ;
Bloom, SR ;
Patel, AG ;
Aylwin, SJB .
BRITISH JOURNAL OF SURGERY, 2006, 93 (02) :210-215
[4]   Are Vitamin B12 and Folate Deficiency Clinically Important after Roux-en-Y Gastric Bypass? [J].
Brolin R.E. ;
Gorman J.H. ;
Gorman R.C. ;
Petschenik A.J. ;
Bradley L.J. ;
Kenler H.A. ;
Cody R.P. .
Journal of Gastrointestinal Surgery, 1998, 2 (5) :436-442
[5]   Bariatric surgery and long-term control of morbid obesity [J].
Brolin, RE .
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 2002, 288 (22) :2793-2796
[6]   Bariatric surgery: A systematic review and meta-analysis [J].
Buchwald, H ;
Avidor, Y ;
Braunwald, E ;
Jensen, MD ;
Pories, W ;
Fahrbach, K ;
Schoelles, K .
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 2004, 292 (14) :1724-1737
[7]   Body-mass index and mortality in a prospective cohort of US adults [J].
Calle, EE ;
Thun, MJ ;
Petrelli, JM ;
Rodriguez, C ;
Heath, CW .
NEW ENGLAND JOURNAL OF MEDICINE, 1999, 341 (15) :1097-1105
[8]   Surgery decreases long-term mortality, morbidity, and health care use in morbidly obese patients [J].
Christou, NV ;
Sampalis, JS ;
Liberman, M ;
Look, D ;
Auger, S ;
McLean, APH ;
MacLean, LD .
ANNALS OF SURGERY, 2004, 240 (03) :416-423
[9]  
Clements RH, 2008, AM SURGEON, V74, P469
[10]  
Clements RH, 2006, AM SURGEON, V72, P1196