Hair trace element contents in women with obesity and type 2 diabetes

被引:53
作者
Skalnaya, Margarita G. [1 ]
Demidov, Vasily A. [1 ]
机构
[1] ANO, Ctr Biot Med, Moscow 105064, Russia
关键词
trace elements; macro elements; obesity; type; 2; diabetes; hair analysis;
D O I
10.1016/j.jtemb.2007.09.019
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
During 2003-2006 totally 1470 women 46-60 y.o., living mainly in Moscow city and Moscow region, were observed. There were three groups of women: obese, diabetic and practically healthy. The anthropometric and clinical data were compared with elemental status, estimated by atomic emission and mass spectroscopy with inductively coupled plasma (ICP-AES/ICP-MS) analyses of occipital scalp hair. The obesity in women was corresponding to elevated hair K, Hg, Pb and decreased Ca, Mg, Zn, I. The type 2 diabetes was corresponding to elevated hair K, Na, Hg and decreased Ca, Mg, Zn, Co. So, the obtained data demonstrate the very similar changes in hair elemental content in both obese and diabetic women, thus suggesting the general pathophysiological mechanisms of metabolic mineral disturbances. (c) 2007 Elsevier GmbH. All rights reserved.
引用
收藏
页码:59 / 61
页数:3
相关论文
共 17 条
[1]   RELATIONSHIPS BETWEEN TRACE-ELEMENTS AND ATHEROSCLEROSIS [J].
AALBERS, TG ;
HOUTMAN, JPW .
SCIENCE OF THE TOTAL ENVIRONMENT, 1985, 43 (03) :255-283
[2]  
[Anonymous], 2004, DIABETES ED S, P2
[3]   Zinc status in plasma of obese individuals during glucose administration [J].
Chen, MD ;
Lin, PY ;
Sheu, WHH .
BIOLOGICAL TRACE ELEMENT RESEARCH, 1997, 60 (1-2) :123-129
[4]   Zinc may be a mediator of leptin production in humans [J].
Chen, MD ;
Song, YM ;
Lin, PY .
LIFE SCIENCES, 2000, 66 (22) :2143-2149
[5]   Determinants of serum copper, zinc and selenium in healthy subjects [J].
Ghayour-Mobarhan, M ;
Taylor, A ;
New, SA ;
Lamb, DJ ;
Ferns, GAA .
ANNALS OF CLINICAL BIOCHEMISTRY, 2005, 42 :364-375
[6]   A Perspective on the Current Strategies for the Treatment of Obesity [J].
Joyal, Steven, V .
CNS & NEUROLOGICAL DISORDERS-DRUG TARGETS, 2004, 3 (05) :341-356
[7]   Relationship between plasma leptin and zinc levels and the effect of insulin and oxidative stress on leptin levels in obese diabetic patients [J].
Konukoglu, D ;
Turhan, MS ;
Ercan, M ;
Serin, O .
JOURNAL OF NUTRITIONAL BIOCHEMISTRY, 2004, 15 (12) :757-760
[8]   Magnesium, insulin resistance and body composition in healthy postmenopausal women [J].
Laires, MJ ;
Moreira, H ;
Monteiro, CP ;
Sardinha, L ;
Limao, F ;
Veiga, L ;
Gonçalves, A ;
Ferreira, A ;
Bicho, M .
JOURNAL OF THE AMERICAN COLLEGE OF NUTRITION, 2004, 23 (05) :510S-513S
[9]  
Mertz W., 1985, Trace elements in nutrition of children. Nestle Nutrition Workshop Series, Volume 8, P107
[10]  
OLUSI S, 2004, BIOL TRACE ELEM RES, V100, P95