Cancer - Encouraging results for second-generation antiangiogenesis drugs

被引:42
作者
Marx, J
机构
关键词
D O I
10.1126/science.308.5726.1248
中图分类号
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号
07 ; 0710 ; 09 ;
摘要
The strategy of denying growing tumors a blood supply continues to show clinical promise as new and improved drugs move through the pipeline. Early last year, the US FDA approved the first cancer drug, an antibody called Avastin, thatis specifically designed to prevent this tumor angiogenesis, as the new bloodvessel growth is called. One advanced clinical trial showed that a new antiangiogenesis drug called, sorafenib significantly slows metastatic kidney cancerand another drug known as Sutent proved its mettle in treating a digestive system cancer called gastrointestinal stromal tumor.
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页码:1248 / 1249
页数:2
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