A structural tree for proteins containing S-like β-sheets

被引：14

作者：

Efimov, AV ^{[1
]}

机构：

[1] Russian Acad Sci, Inst Prot Res, Pushchino 142292, Moscow Region, Russia

来源：

FEBS LETTERS | 1998年 / 437卷 / 03期

基金：

俄罗斯基础研究基金会;

关键词：

protein classification; protein structure modelling; stepwise folding; structural motif; structural similarity;

D O I：

10.1016/S0014-5793(98)01244-7

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

A structural tree for proteins and domains containing S-like beta-sheets has been constructed. An S-like beta-sheet is taken as a starting structure in modelling or as a root structure of the tree. Larger structures are obtained by a stepwise addition of It strands and/or alpha-helices to the root S-like beta-sheet in accordance with a restricted set of rules inferred from known principles of protein structure. Applications of the structural tree to structure comparison, protein classification and protein folding are described. (C) 1998 Federation of European Biochemical Societies.

引用

页码：246 / 250

页数：5

共 34 条

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