Catalonian population study of the tetranucleotide repeat loci D3S1358, D8S1179, D18S51 and D19S253

被引：11

作者：

Gené, M

Piqué, E

Borrego, N

Carracedo, A

Huguet, E

Moreno, P

机构：

[1] Univ Barcelona, Fac Med, Dept Legal Med, Forens Genet Lab, E-08036 Barcelona, Spain

[2] Univ Santiago, Fac Med, Inst Legal Med, E-15705 Santiago De Compostela, Spain

[3] Univ Barcelona, Fac Biol, Sect Anthropol, Dept Anim Biol, E-08028 Barcelona, Spain

来源：

INTERNATIONAL JOURNAL OF LEGAL MEDICINE | 1998年 / 112卷 / 01期

关键词：

D3S1358; D8S1179; D18S51; D19S253; triplex PCR amplification; forensic genetics;

D O I：

10.1007/s004140050205

中图分类号：

DF [法律]; D9 [法律]; R [医药、卫生];

学科分类号：

0301 ; 10 ;

摘要：

Allele frequencies for four short tandem repeat loci were determined in a population sample from Catalonia (NE Spain). After denaturing PAGE electrophoresis, 8 alleles were identified for D3S1358 (n = 20), 10 alleles for D8S1179 (n = 198), 13 alleles for D18S51 (n = 197) and 11 alleles for D19S253 (n = 201). No deviation from Hardy-Weinberg equilibrium was found. Complete and relative uniformity in Caucasoid populations has been observed for D18S51 and D8S1179 respectively. Pronounced differences were found between different ethnic groups for both systems. Catalonia and Portugal do not differ for D3S1358 locus. Multiplex PCR amplifications of three loci (D3S1358, D18S51 and D19S253) without overlapping fragment size ranges could be interesting for monochrome automated laser fluorescence devices.

引用

页码：75 / 77

页数：3

共 14 条

[1]

[Anonymous], 1992, Int J Legal Med, V105, P63

[2]

Evett IW, 1997, INT J LEGAL MED, V110, P5

[3]

Fisher R. A., 1932, STAT METHODS RES WOR, DOI DOI 10.1007/978-1-4612-4380-9_6

[4] STANDARD CALCULATIONS FOR EVALUATING A BLOOD-GROUP SYSTEM [J].