Preferential solvation and hydrogen bonding in mixed solvents

被引：47

作者：

Cook, Joanne L. ^{[1
]}

Hunter, Christopher A. ^{[1
]}

Low, Caroline M. R. ^{[2
]}

Perez-Velasco, Alejandro ^{[1
]}

Vinter, Jeremy G. ^{[3
]}

机构：

[1] Univ Sheffield, Dept Chem, Sheffield S3 7HF, S Yorkshire, England

[2] Univ London Imperial Coll Sci Technol & Med, Drug Discovery Facil, London SW7 2AY, England

[3] Cresset Biomol Discovery, Letchworth SG6 4ET, England

来源：

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | 2008年 / 47卷 / 33期

基金：

英国工程与自然科学研究理事会; 英国生物技术与生命科学研究理事会;

关键词：

hydrogen bonds; molecular recognition; NMR spectroscopy; solvation; solvent mixtures;

D O I：

10.1002/anie.200801349

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

(Chemical Equation Presented) Oak trees from acorns: A small amount (< 1%) of a cosolvent can change the stability of the H-bonded complex on the right-hand side of the equation by an order of magnitude. Mixtures of chloroform and THF were found to be more polar than either of the pure solvents by using this complex as a molecular-recognition probe of solvation. A quantitative interpretation based on preferential solvation accounts for the properties of solvent mixtures. © 2008 Wiley-VCH Verlag GmbH & Co. KGaA.

引用

页码：6275 / 6277

页数：3

共 18 条

[1]

Ben-Naim A., 1987, SOLVATION THERMODYNA

[2] PREFERENTIAL SOLVATION IN MIXED BINARY SOLVENTS - ULTRAVIOLET-VISIBLE SPECTROSCOPY OF N-ALKYLPYRIDINIUM IODIDES IN MIXED-SOLVENTS CONTAINING CYCLIC ETHERS [J].

CHATTERJEE, P ;

LAHA, AK ;

BAGCHI, S .

JOURNAL OF THE CHEMICAL SOCIETY-FARADAY TRANSACTIONS, 1992, 88 (12) :1675-1678

[3]

Cook J. L., 2007, ANGEW CHEM, V119, P3780

[4] Solvent effects on hydrogen bonding [J].

Cook, Joanne L. ;

Hunter, Christopher A. ;

Low, Caroline M. R. ;

Perez-Velasco, Alejandro ;

Vinter, Jeremy G. .

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2007, 46 (20) :3706-3709

[5] UV-visible spectroscopic study of the hydrophilic and solvatoichromic-4-[2,6-diphenyl-4-(pyridin-4-yl) pyridinium-1-yl]-2,6-bis(pyridin-3-yl)phenolate betaine dye in eight binary solvent mixtures [J].

Herodes, K ;

Koppel, J ;

Reichardt, C ;

Koppel, IA .

JOURNAL OF PHYSICAL ORGANIC CHEMISTRY, 2003, 16 (09) :626-632

[6]

Hildebrand JH, 1970, REGULAR RELATED SOLU, DOI DOI 10.1016/S0006-4971(20)78019-5

[7] Quantifying intermolecular interactions: Guidelines for the molecular recognition toolbox [J].

Hunter, CA .

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2004, 43 (40) :5310-5324

[8] EMPIRICAL PARAMETERS OF LEWIS ACIDITY AND BASICITY FOR AQUEOUS BINARY SOLVENT MIXTURES [J].

KRYGOWSKI, TM ;

WRONA, PK ;

ZIELKOWSKA, U ;

REICHARDT, C .

TETRAHEDRON, 1985, 41 (20) :4519-4527

[9] POLARITY OF BINARY-LIQUID MIXTURES [J].

LANGHALS, H .

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION IN ENGLISH, 1982, 21 (10) :724-733

[10]

Langhals H., 1982, Angew Chem, V94, P739

← 1 2 →