An enantioselective synthesis of insecticidal 4-alkynyloxazolines

被引：25

作者：

Clark, D ^{[1
]}

Travis, DA ^{[1
]}

机构：

[1] DuPont Crop Protect, Stine Haskell Res Ctr, Newark, DE 19714 USA

来源：

BIOORGANIC & MEDICINAL CHEMISTRY | 2001年 / 9卷 / 11期

关键词：

D O I：

10.1016/S0968-0896(01)00153-5

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

2-(2,6-Difluorophenyl)-4-phenylalkynyl oxazolines are potent insect growth regulators. An efficient and enantioselective synthesis to these compounds has been developed which relies on a (-)-sparteine mediated hydroxymethylation of the lithium dianion of propargylic amides. (C) 2001 Elsevier Science Ltd. All rights reserved.

引用

页码：2857 / 2862

页数：6

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