Selective ortho hydroxylation of nitrobenzene with molecular oxygen catalyzed by the H5PV2Mo10O40 polyoxometalate

被引：65

作者：

Khenkin, AM

Weiner, L

Neumann, R ^{[1
]}

机构：

[1] Weizmann Inst Sci, Dept Organ Chem, IL-76100 Rehovot, Israel

[2] Weizmann Inst Sci, Chem Res Support Unit, IL-76100 Rehovot, Israel

来源：

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY | 2005年 / 127卷 / 28期

关键词：

D O I：

10.1021/ja051286g

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Nitrobenzene was regioselectively oxidized to 2-nitrophenol with oxygen in a reaction catalyzed by the H5PV2Mo10O40 polyoxometalate. The reaction was first order in oxygen and catalyst. 15N NMR showed the interaction between nitrobenzene and the polyoxometalate. Use of labeled 18O2, H218O, a competitive kinetic isotope experiment, and use of phenyl-tert-butylnitrone as a spin-trap and identification by EPR provided evidence for formation of a radical intermediate involving a selective intramolecular interaction at the ortho position due to formation of a H5PV2Mo10O40-nitrobenzene complex. Copyright © 2005 American Chemical Society.

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页码：9988 / 9989

页数：2

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